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Japan Approved Orladeyo for Under-Twelves in an Open-Label Interim Analysis of 29 Children
Japan Approved Orladeyo for Under-Twelves in an Open-Label Interim Analysis of 29 Children
Athithi Verma August 26, 2026
The molecule has been approved in Japan since 2021. What is new is a formulation a two-year-old can swallow, and that is the commercial move.
A Dual MYC and GSPT1 Degrader Extended Survival by Over 300% in One Preclinical Model
A Dual MYC and GSPT1 Degrader Extended Survival by Over 300% in One Preclinical Model
China Will Pay One Price for 158 Conditions Whatever the Hospital. Most of Them Are Drug-Led.
China Will Pay One Price for 158 Conditions, Whatever the Hospital
France Funded Two Cancer Drugs the Same Week. One Was Rated Therapeutic Progress, One Was Not.
France Funded Two Cancer Drugs the Same Week. One Was Rated Therapeutic Progress, One Was Not.
Avulux Won a De Novo and Created the Category Its Competitors Will File Into
Avulux Won a De Novo and Created the Category Its Competitors Will File Into
ASCO's First ctDNA Guideline Found Few Instances of Clinical Utility. Residual Disease Got No Recommendation at All.
ASCO’s First ctDNA Guideline Found Few Instances of Clinical Utility. Residual Disease Got No Recommendation at All.

Editor’s Pick

In Ustekinumab Biosimilars, Approval Stopped Being the Hard Part

In Ustekinumab Biosimilars, Approval Stopped Being the Hard Part

In Japan, Expanding a Label Is What Triggers the Price Cut

In Japan, Expanding a Label Is What Triggers the Price Cut

AstraZeneca Announced Nothing. The Market Charged It $24bn Anyway.

AstraZeneca Announced Nothing. The Market Charged It $24bn Anyway.

NeuroPulse


NeuroPulse Wk 33: Jazz Bet $820M on a New FDA Evidence Standard

NeuroPulse Wk 33: Jazz Bet $820M on a New FDA Evidence Standard

NeuroPulse Wk 32: Takeda Fixed the Cause, and Cannot Ship It Yet

NeuroPulse Wk 32: Takeda Fixed the Cause, and Cannot Ship It Yet

OrphanPulse


OrphanPulse Wk 33: The Competitor Got a PDUFA Date Five Days Later

OrphanPulse Wk 33: The Competitor Got a PDUFA Date Five Days Later

OrphanPulse Wk 32: Tarsus Paid $450M Upfront for a Readout in 2029

OrphanPulse Wk 32: Tarsus Paid $450M Upfront for a Readout in 2029

DealPulse Signal


DealPulse Signal Wk 33: Rare Disease Took Two Thirds of the Week

DealPulse Signal Wk 33: Rare Disease Took Two Thirds of the Week

DealPulse Signal Wk 32: Private Equity Took the Week and Paid Cash for All of It

DealPulse Signal Wk 32: Private Equity Took the Week and Paid Cash for All of It

DealPulse Report


DealPulse Report July 2026: Vertex Pays 102% as Oncology Cedes the Lead

DealPulse Report July 2026: Vertex Pays 102% as Oncology Cedes the Lead

DealFlow H1 2026 M&A Doubles as Upfront Spending Hits $174B

DealFlow H1 2026: M&A Doubles as Upfront Spending Hits $174B

The Beats


DealPulse Signal Wk 33: Rare Disease Took Two Thirds of the Week

DealPulse Signal Wk 33: Rare Disease Took Two Thirds of the Week

DealPulse Signal Wk 32: Private Equity Took the Week and Paid Cash for All of It

DealPulse Signal Wk 32: Private Equity Took the Week and Paid Cash for All of It

DealPulse Report July 2026: Vertex Pays 102% as Oncology Cedes the Lead

DealPulse Report July 2026: Vertex Pays 102% as Oncology Cedes the Lead

Analysis


Reshaping Pharma by 2027

7 Market Access Trends Reshaping Pharmaย by 2027

The Biologics Patent Cliff: Inside Pharma's 2026-2029 Reckoning

The Biologics Patent Cliff: Inside Pharma’s 2026-2029 Reckoning

Coverage


The ADC Decade Accelerates What to Watch at ASCO 2026

The ADC Decade Accelerates: What to Watch at ASCO 2026

The Briefs

Japan Approved Orladeyo for Under-Twelves in an Open-Label Interim Analysis of 29 Children

Japan Approved Orladeyo for Under-Twelves in an Open-Label Interim Analysis of 29 Children

Athithi Verma August 26, 2026
A Dual MYC and GSPT1 Degrader Extended Survival by Over 300% in One Preclinical Model

A Dual MYC and GSPT1 Degrader Extended Survival by Over 300% in One Preclinical Model

Athithi Verma August 26, 2026
China Will Pay One Price for 158 Conditions Whatever the Hospital. Most of Them Are Drug-Led.

China Will Pay One Price for 158 Conditions, Whatever the Hospital

Athithi Verma August 26, 2026
France Funded Two Cancer Drugs the Same Week. One Was Rated Therapeutic Progress, One Was Not.

France Funded Two Cancer Drugs the Same Week. One Was Rated Therapeutic Progress, One Was Not.

Athithi Verma August 26, 2026
Avulux Won a De Novo and Created the Category Its Competitors Will File Into

Avulux Won a De Novo and Created the Category Its Competitors Will File Into

Athithi Verma August 26, 2026
ASCO's First ctDNA Guideline Found Few Instances of Clinical Utility. Residual Disease Got No Recommendation at All.

ASCO’s First ctDNA Guideline Found Few Instances of Clinical Utility. Residual Disease Got No Recommendation at All.

Athithi Verma August 25, 2026
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