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A Custom ALS Drug Took Three Years to Build and One Year to Normalise One Man's Neurofilament
A Custom ALS Drug Took Three Years to Build and One Year to Normalise One Man’s Neurofilament
Admin September 21, 2026
Built in about three years for one mutation, it normalised a biomarker in one man. A larger cohort sits outside the paper.
UnitedHealthcare Is Enlisting Doctors Against the Paperwork Behind 43% of Projected Medicaid Losses
UnitedHealthcare Is Enlisting Doctors Against the Paperwork Behind 43% of Projected Medicaid Losses
China Ordered Rare Disease Clinics in Every Province by December and Left Payment Out
China Ordered Rare Disease Clinics in Every Province by December and Left Payment Out
Merck Moved Every Japanese Keytruda Indication to a One-Minute Injection on a Single Lung Cancer Trial
Merck Moved Every Japanese Keytruda Indication to a One-Minute Injection on a Single Lung Cancer Trial
Telix Is Paying $1.65 Billion for ITM Without Handing the Sellers Any Cash at Closing
Telix Is Paying $1.65 Billion for ITM Without Handing the Sellers Any Cash at Closing
India Got Three Different Access Mechanisms in Four Days
India Got Three Different Access Mechanisms in Four Days

Editor’s Pick

Rare Disease Produced Two First-Ever Approvals in Two Days, and Both of Them Are Neurology

Rare Disease Produced Two First-Ever Approvals in Two Days, and Both of Them Are Neurology

In Ustekinumab Biosimilars, Approval Stopped Being the Hard Part

In Ustekinumab Biosimilars, Approval Stopped Being the Hard Part

In Japan, Expanding a Label Is What Triggers the Price Cut

In Japan, Expanding a Label Is What Triggers the Price Cut

NeuroPulse


NeuroPulse Wk 38: Xenon Filed in Epilepsy and Paused in Psychiatry on the Same Day

NeuroPulse Wk 38: Xenon Filed in Epilepsy and Paused in Psychiatry on the Same Day

NeuroPulse Wk 33: Jazz Bet $820M on a New FDA Evidence Standard

NeuroPulse Wk 33: Jazz Bet $820M on a New FDA Evidence Standard

OrphanPulse


OrphanPulse Wk 38: Two Untreatable Childhood Diseases Got First Therapies in 24 Hours

OrphanPulse Wk 38: Two Untreatable Childhood Diseases Got First Therapies in 24 Hours

OrphanPulse Wk 33: The Competitor Got a PDUFA Date Five Days Later

OrphanPulse Wk 33: The Competitor Got a PDUFA Date Five Days Later

DealPulse Signal


DealPulse Signal Wk 33: Rare Disease Took Two Thirds of the Week

DealPulse Signal Wk 33: Rare Disease Took Two Thirds of the Week

DealPulse Signal Wk 32: Private Equity Took the Week and Paid Cash for All of It

DealPulse Signal Wk 32: Private Equity Took the Week and Paid Cash for All of It

DealPulse Report


DealPulse Report July 2026: Vertex Pays 102% as Oncology Cedes the Lead

DealPulse Report July 2026: Vertex Pays 102% as Oncology Cedes the Lead

DealFlow H1 2026 M&A Doubles as Upfront Spending Hits $174B

DealFlow H1 2026: M&A Doubles as Upfront Spending Hits $174B

The Beats


DealPulse Signal Wk 33: Rare Disease Took Two Thirds of the Week

DealPulse Signal Wk 33: Rare Disease Took Two Thirds of the Week

DealPulse Signal Wk 32: Private Equity Took the Week and Paid Cash for All of It

DealPulse Signal Wk 32: Private Equity Took the Week and Paid Cash for All of It

DealPulse Report July 2026: Vertex Pays 102% as Oncology Cedes the Lead

DealPulse Report July 2026: Vertex Pays 102% as Oncology Cedes the Lead

Analysis


Radiopharmaceuticals: sixteen years of deal data on where the field goes next

Radiopharmaceuticals: sixteen years of deal data on where the field goes next

Behind the Headlines How the Leaders Really Performed

Behind the Headlines: How the Leaders Really Performed

Reshaping Pharma by 2027

7 Market Access Trends Reshaping Pharmaย by 2027

Coverage


ADCs Returned 0.46 in Relapsed Disease and 1.15 in the Front Line at WCLC

The ADC Decade Accelerates What to Watch at ASCO 2026

The ADC Decade Accelerates: What to Watch at ASCO 2026

The Briefs

A Custom ALS Drug Took Three Years to Build and One Year to Normalise One Man's Neurofilament

A Custom ALS Drug Took Three Years to Build and One Year to Normalise One Man’s Neurofilament

Admin September 21, 2026
UnitedHealthcare Is Enlisting Doctors Against the Paperwork Behind 43% of Projected Medicaid Losses

UnitedHealthcare Is Enlisting Doctors Against the Paperwork Behind 43% of Projected Medicaid Losses

Admin September 21, 2026
China Ordered Rare Disease Clinics in Every Province by December and Left Payment Out

China Ordered Rare Disease Clinics in Every Province by December and Left Payment Out

Admin September 21, 2026
Merck Moved Every Japanese Keytruda Indication to a One-Minute Injection on a Single Lung Cancer Trial

Merck Moved Every Japanese Keytruda Indication to a One-Minute Injection on a Single Lung Cancer Trial

Admin September 21, 2026
Telix Is Paying $1.65 Billion for ITM Without Handing the Sellers Any Cash at Closing

Telix Is Paying $1.65 Billion for ITM Without Handing the Sellers Any Cash at Closing

Admin September 21, 2026
India Got Three Different Access Mechanisms in Four Days

India Got Three Different Access Mechanisms in Four Days

Athithi Verma September 21, 2026
Read More
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