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OrphanPulse Wk 40: A First Approval in MCT8 Deficiency, and a Missed Pivotal Headed for Filing
OrphanPulse Wk 40: A First Approval in MCT8 Deficiency, and a Missed Pivotal Headed for Filing
Athithi Verma October 5, 2026
One first approval, and one missed pivotal headed for filing anyway: the week tested what rare disease evidence can carry.
Merck and Daiichi Pulled an ADC Filing as GSK Paid $110 Million for a KRAS Payload
Merck and Daiichi Pulled an ADC Filing as GSK Paid $110 Million for a KRAS Payload
ICER Says AstraZeneca's $10,950 Baxfendy Is Worth $1,400 to $2,500 a Year
ICER Says AstraZenecaโ€™s $10,950 Baxfendy Is Worth $1,400 to $2,500 a Year
Genentech Paid $100 Million for Alector's Parkinson's Enzyme but Not Its Brain Shuttle
Genentech Paid $100 Million for Alector’s Parkinson’s Enzyme but Not Its Brain Shuttle
Shionogi Paid 29 Times Sales for IntraBio, 17 Days After AQNEURSA's Second FDA Approval
Shionogi Paid 29 Times Sales for IntraBio, 17 Days After AQNEURSA’s Second FDA Approval
CSL Paid $355 Million and Gave Up 45% of the Profits to Win a Claudin-1 Antibody
CSL Paid $355 Million and Gave Up 45% of the Profits to Win a Claudin-1 Antibody

Editor’s Pick

Rare Disease Produced Two First-Ever Approvals in Two Days, and Both of Them Are Neurology

Rare Disease Produced Two First-Ever Approvals in Two Days, and Both of Them Are Neurology

In Ustekinumab Biosimilars, Approval Stopped Being the Hard Part

In Ustekinumab Biosimilars, Approval Stopped Being the Hard Part

In Japan, Expanding a Label Is What Triggers the Price Cut

In Japan, Expanding a Label Is What Triggers the Price Cut

NeuroPulse


NeuroPulse Wk 40: AbbVie Won Approval for Juvmo Three Days Before ICER Met on Its Value

NeuroPulse Wk 40: AbbVie Won Approval for Juvmo Three Days Before ICER Met on Its Value

NeuroPulse Wk 39: Otsuka Opened Early Access the Day Before FUS-ALS Read Out

NeuroPulse Wk 39: Otsuka Opened Early Access the Day Before FUS-ALS Read Out

OrphanPulse


OrphanPulse Wk 40: A First Approval in MCT8 Deficiency, and a Missed Pivotal Headed for Filing

OrphanPulse Wk 40: A First Approval in MCT8 Deficiency, and a Missed Pivotal Headed for Filing

OrphanPulse Wk 39: A 900-Patient Disease Now Has Two Approved Drugs

OrphanPulse Wk 39: A 900-Patient Disease Now Has Two Approved Drugs

DealPulse Signal


DealPulse Signal Wk 39: Telix Paid in Stock and the Platforms Paid in Promises

DealPulse Signal Wk 39: Telix Paid in Stock and the Platforms Paid in Promises

DealPulse Signal Wk 33: Rare Disease Took Two Thirds of the Week

DealPulse Signal Wk 33: Rare Disease Took Two Thirds of the Week

DealPulse Report


DealPulse Report July 2026: Vertex Pays 102% as Oncology Cedes the Lead

DealPulse Report July 2026: Vertex Pays 102% as Oncology Cedes the Lead

DealFlow H1 2026 M&A Doubles as Upfront Spending Hits $174B

DealFlow H1 2026: M&A Doubles as Upfront Spending Hits $174B

The Beats


DealPulse Signal Wk 39: Telix Paid in Stock and the Platforms Paid in Promises

DealPulse Signal Wk 39: Telix Paid in Stock and the Platforms Paid in Promises

DealPulse Signal Wk 33: Rare Disease Took Two Thirds of the Week

DealPulse Signal Wk 33: Rare Disease Took Two Thirds of the Week

DealPulse Signal Wk 32: Private Equity Took the Week and Paid Cash for All of It

DealPulse Signal Wk 32: Private Equity Took the Week and Paid Cash for All of It

Analysis


Radiopharmaceuticals: sixteen years of deal data on where the field goes next

Radiopharmaceuticals: sixteen years of deal data on where the field goes next

Behind the Headlines How the Leaders Really Performed

Behind the Headlines: How the Leaders Really Performed

Reshaping Pharma by 2027

7 Market Access Trends Reshaping Pharmaย by 2027

Coverage


ADCs Returned 0.46 in Relapsed Disease and 1.15 in the Front Line at WCLC

The ADC Decade Accelerates What to Watch at ASCO 2026

The ADC Decade Accelerates: What to Watch at ASCO 2026

The Briefs

Merck and Daiichi Pulled an ADC Filing as GSK Paid $110 Million for a KRAS Payload

Merck and Daiichi Pulled an ADC Filing as GSK Paid $110 Million for a KRAS Payload

Athithi Verma October 5, 2026
ICER Says AstraZeneca's $10,950 Baxfendy Is Worth $1,400 to $2,500 a Year

ICER Says AstraZenecaโ€™s $10,950 Baxfendy Is Worth $1,400 to $2,500 a Year

Athithi Verma October 5, 2026
Genentech Paid $100 Million for Alector's Parkinson's Enzyme but Not Its Brain Shuttle

Genentech Paid $100 Million for Alector’s Parkinson’s Enzyme but Not Its Brain Shuttle

Athithi Verma October 5, 2026
Shionogi Paid 29 Times Sales for IntraBio, 17 Days After AQNEURSA's Second FDA Approval

Shionogi Paid 29 Times Sales for IntraBio, 17 Days After AQNEURSA’s Second FDA Approval

Athithi Verma October 5, 2026
CSL Paid $355 Million and Gave Up 45% of the Profits to Win a Claudin-1 Antibody

CSL Paid $355 Million and Gave Up 45% of the Profits to Win a Claudin-1 Antibody

Athithi Verma October 5, 2026
Merck Has 26 Months to Move Keytruda Patients to a Shot Protected Until 2043

Merck Has 26 Months to Move Keytruda Patients to a Shot Protected Until 2043

Athithi Verma October 5, 2026
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