NICE Backs Finerenone for 280,000 Heart Failure Patients

NICE Backs Finerenone for 280,000 Heart Failure Patients

Half of England’s heart failure patients have spent decades watching the other half get all the drugs. That’s the context for what NICE did this week. On 16 July, the institute published final draft guidance recommending finerenone for adults with chronic heart failure with preserved or mildly reduced ejection fraction. NICE estimates up to 280,000 … Read more

DealFlow H1 2026: M&A Doubles as Upfront Spending Hits $174B

DealFlow H1 2026 M&A Doubles as Upfront Spending Hits $174B

DealFlow H1 2026 Review: M&A Rebounds as Upfront Deal Spending Doubles Synopulse · DealFlow · Healthcare & life sciences dealmaking · H1 2026 review M&A came back big, and wrote the cheque in cash M&A value rose 96% to $188 billion in the first half of 2026 and upfront payments jumped 72%, as acquirers paid … Read more

Germany Defies Pharma Backlash, Hikes Drug Rebate to 15.5%

Germany has passed healthcare reforms despite pharma's resistance, hiking the fixed rebate on branded drugs from 7% to 15.5% to save €16.3 billion next year.

Germany’s lawmakers had no shortage of warnings. Drugmakers objected. Trade groups objected. So did opposition voices inside the country’s own government. The reform passed anyway. Late on Friday, the Bundestag, Germany’s lower house of parliament, approved a health insurance financial reform package by 318 votes to 284, with four abstentions. That is not a comfortable … Read more

The Pulse – Biopharma Week in Review: Vertex’s $10B Deal, Keytruda Bladder Win

The Pulse - Biopharma this Week (july 6 - 12, 2026)

The Pulse – Weekly biopharma intelligence – Synopulse Synopulse The Pulse Synopulse’s weekly biopharma briefing – deals, approvals, readouts and access, across every therapy area. WEEKLY6 – 12 July 2026Wk 28 · 2026 The Hub Neurology19 Onco+Immuno30 CardioMeta17 Approvals The big events this week Deal Vertex acquires Crinetics for $10 billion The week’s largest transaction … Read more

AlzeCure Pharma Secures a $2.2B QuantumCell Deal for Its NeuroRestore Platform

AlzeCure Pharma Secures a $2.2B QuantumCell Deal for Its NeuroRestore Platform

AlzeCure Pharma has found a partner for its Alzheimer’s program, and the numbers attached to the deal are eye-catching, though not all of them in the way the headline suggests. The Swedish biotech said on July 1 that it has signed an out-licensing and collaboration agreement with QuantumCell, a Danish “tech-enabled” biotech, handing over global … Read more