Behind the Headlines: How the Leaders Really Performed

Synopulse · The Top Line · Q2 2026

Behind the Headlines: How the Leaders Really Performed

Athithi Verma·8 September 2026·Quarterly edition·Synopulse

Thirty companies, one quarter. Read together rather than one at a time, the quarter divides along four lines, and none of them is visible in a headline growth rate.

The first is currency, which decided the reported number in opposite directions. Roche’s business grew 6 percent at constant rates and the Swiss franc turned that into a 2 percent decline. Takeda’s shrank 0.5 percent and the yen turned it into 10.2 percent growth. Alongside them, three imaging and device majors reported margins lifted by United States tariff refunds, and Philips put a figure on it: 4.2 points of a 4.0 point margin gain.

The second is succession, and this is the quarter several handovers crossed. AbbVie’s Skyrizi added more revenue in three months than Humira has left to sell. Teva’s AUSTEDO overtook the entire United States generics business the company was built on. Merck’s Keytruda went backwards and its own subcutaneous version covered the gap. At Johnson & Johnson, Oncology grew by more than STELARA lost; at Novartis, the same test failed by $14 million.

The third is concentration. Dupixent is 44 percent of Sanofi and four fifths of its growth. HIV is 75 percent of Gilead’s product sales. Keytruda and its successor together are half of Merck. The fourth is what the statutory accounts hide: Gilead booked an $11.2 billion charge against $7.8 billion of quarterly revenue, and GSK’s total operating profit fell 76 percent on a single impairment while its core measure rose 6 percent.

Entries are numbered by market capitalisation at 30 June 2026, which sets the reading order and nothing else. Conglomerate entries cover the healthcare and life science business only, and that scope is stated on every card.

01 Beat · sales up, EPS range cut

Revenue grew 48 percent and the top of the earnings range still came down

Lilly added $7,416 million of revenue in a single quarter, taking sales to $22,974 million against $15,558 million a year earlier. Two products did almost all of it. Mounjaro reached $9,943 million, up 91 percent, and Zepbound $4,928 million, up 46 percent. Together they are $14,871 million, which is 64.7 percent of everything the company sold.

Then the guidance moved in two directions at once. Lilly raised the revenue range from $82 to $85 billion up to $85 to $87 billion, and cut the top of the earnings per share range from $37.00 to $36.50. The reason sits in one line of the income statement: acquired in-process research and development of $2,776 million against $154 million a year ago, worth $3.03 a share.

The buying explains the charge. Lilly signed a development and commercialisation deal with Abbisko worth up to $1,900 million, took BioArctic’s neurodegeneration programme for $30 million upfront against $800 million in total, bought Sangamo’s ST-506 outright for $50 million and acquired 4E Therapeutics. Three of those four are neurology, which is the smallest of its four therapy areas at $429 million.

01Mkt cap Eli Lilly NYSE LLY · Mkt cap USD 1.14T
Total revenue
USD 22.97B
+47.7%reported
Revenue added
+USD 7.42B
From USD 15.56B, +47.7%
Profit margin
39.1%-503bp
Operating margin, from 44.1%
R&D expense
USD 3.82B+14.5%
16.6% of sales, from 21.4%
Adjusted EPS
USD 8.38+32.8%
Reported USD 7.94, from USD 6.29
Gross margin
85.8%+151bp
Gross profit USD 19.71B
Sales by region · as reported
USD 22.97B Q2 SALES
United StatesUSD 14.41B · +18.9% vs Q162.7%
InternationalUSD 8.56B · +11.5% vs Q137.3%
Therapy area · sequential on Q1 2026
CardiometabolicUSD 18.35B+16.5%
OncologyUSD 2.57B+13.3%
ImmunologyUSD 1.42B+17.8%
NeuroscienceUSD 429M+12.3%
OtherUSD 205M+9.6%
The swing · year on year
Acquired IPR&D charged-USD 2.78B
Revenue added+USD 7.42B
Revenue grew USD 7.42B and the top of the EPS range still came down. Acquired IPR&D of USD 2.78B cost USD 3.03 a share against USD 0.14 a year ago.
Top 5 · by revenue
MounjaroCardiometabolicUSD 9.94B+91%
ZepboundCardiometabolicUSD 4.93B+46%
VerzenioOncologyUSD 1.47B
TaltzImmunologyUSD 856M
OlumiantImmunologyUSD 258M
Launches · year on year
EbglyssImmunologyUSD 201M+131%
JaypircaOncologyUSD 192M+56%
Kisunlafrom USD 49MUSD 167M+241%
OmvohImmunologyUSD 102M+36%
Foundayofirst quarterUSD 98M
Deals & capital
  • Abbisko development and commercialisation licence USD 1.9B total
  • BioArctic neurodegeneration programme USD 30M up, USD 800M total
  • Sangamo ST-506 product purchase, neurology USD 50M
  • 4E Therapeutics acquired, neurology, terms not disclosed
Where the money went
  • Acquired IPR&D USD 2,776M against USD 154M, worth USD 3.03 a share
  • Research and development USD 3.82B, up 14.5%, 16.6% of sales from 21.4%
  • Marketing, selling, admin USD 3.43B, up 24.6%, 14.9% of sales
  • Operating income USD 8.98B, up 30.7%, a 39.1% margin
On the clock · next quarter
  • WatchEPS range top cut to USD 36.50 while the revenue range rose USD 3B
  • WatchConcentration Mounjaro and Zepbound are 64.7% of sales
  • WatchNeurology four deals in fifteen days, against a USD 429M therapy area
  • WatchTax rate 23.3% against 16.5%, seven points of earnings drag
SG&A USD 3.43B, 14.9% of sales, +24.6%/Cost of sales USD 3.27B, 14.2%/Acquired IPR&D USD 2.78B from USD 154M/Operating income USD 8.98B, 39.1%, +30.7%/Pre-tax USD 9.25B/Net income USD 7.09B, +25.3%
Synopulse
The Top Line · Q2 2026
Q2 2026 results release · extracted 20 August 2026
What decides the next twelve months Whether the acquired IPR&D line settles. Revenue guidance went up $3 billion and the earnings range came down, and the gap between those two moves is deal charges, not demand. Mounjaro and Zepbound are 64.7 percent of sales, so the concentration risk is real even while both compound. The neurology buying spree, four deals in fifteen days, is the company trying to build a second leg before it needs one.
02 Beat · guidance raised

One franchise grew by more than the company’s biggest loss of exclusivity took away

J&J passed $25 billion in a quarter for the first time in its 140-year history, and the number that explains it is not the headline. It is STELARA, down 55.2 percent to $740 million from $1,653 million. The product shed $913 million of quarterly revenue against the same period last year, a hole close to a billion dollars wide in a single line item.

Oncology filled it and then some. The franchise grew 17.3 percent to $7,406 million, adding $1,094 million year on year, more than STELARA lost. That is the entire loss-of-exclusivity defence in two figures, and it is why guidance went up rather than sideways. Look one level further and the scale of the shift is clearer still: DARZALEX alone, at $4,207 million, is now larger than J&J’s whole Immunology therapy area at $3,844 million. A single product has outgrown a franchise.

Immunology still fell 3.7 percent, which is the honest counterweight. TREMFYA at $2,046 million is growing 72.5 percent and carrying the segment, but not yet fast enough to absorb what STELARA is giving up. The successor was in market before the cliff arrived, which is the part of the playbook J&J executed correctly; the arithmetic simply has not caught up yet.

The deal sheet says the same thing. J&J paid $1,000 million for Firefly Bio in June to buy a degrader antibody conjugate platform for Oncology, and in April sold botaretigene sparoparvovec back to MeiraGTx for $25 million upfront against $75 million total. A billion dollars into oncology chemistry, an ophthalmic gene therapy on the way out.

02Mkt cap Johnson & Johnson NYSE JNJ · Mkt cap USD 658.89B
Total revenue
USD 25.31B
+6.6%reported+5.6%operational
Revenue added
+USD 1.57B
From USD 23.74B, +6.6%
Profit margin
26.7%
Pre-tax margin, USD 6.75B
R&D expense
USD 3.65B+3.9%
14.4% of sales, from 14.8%
Adjusted EPS
USD 2.90+4.7%
Reported USD 2.27, from USD 2.29
Gross margin
68.2%+30bp
Gross profit USD 17.26B
Sales by region · as reported
USD 25.31B Q2 SALES
United StatesUSD 14.53B · +7.3% op57.4%
EuropeUSD 5.73B · +3.3% op22.6%
Asia-Pacific, AfricaUSD 3.74B · +3.9% op14.8%
Western Hem. ex-USUSD 1.31B · +2.7% op5.2%
Franchise growth · sized on largest
Innovative Medicine USD 16.38B +7.8%MedTech USD 8.93B +4.5%
OncologyInnov MedUSD 7.41B+17.3%
ImmunologyInnov MedUSD 3.84B-3.7%
PH, ID, CVMInnov MedUSD 2.79B-1.8%
NeuroscienceInnov MedUSD 2.34B+13.9%
SurgeryMedTechUSD 2.65B+3.8%
OrthopaedicsMedTechUSD 2.42B+4.9%
CardiovascularMedTechUSD 2.4B+3.9%
VisionMedTechUSD 1.45B+6.0%
The swing · year on year
STELARA-USD 913M
Oncology franchise+USD 1.09B
One franchise covered the largest biosimilar loss in the portfolio and left USD 181M over. STELARA cost Innovative Medicine 760 basis points of growth and the segment still grew 6.8% operationally.
Top 5 · Innovative Medicine
DARZALEXOncologyUSD 4.21B+18.9%
TREMFYAImmunologyUSD 2.05B+72.5%
INVEGA TRINZA / TREVICTANeuroUSD 1.01B+2.3%
ERLEADAOncologyUSD 995M+9.5%
STELARAbiosimilar hitUSD 740M-55.2%
MedTech · four franchises
Surgeryadvanced + generalUSD 2.65B+3.8%
OrthopaedicsseparatingUSD 2.42B+4.9%
CardiovascularEP USD 1.53B insideUSD 2.4B+3.9%
Visioncontact lenses ledUSD 1.45B+6.0%
MedTech totalsegmentUSD 8.93B+4.5%
Cleared this quarter
  • TREMFYA FDA label expansion, structural joint damage in psoriatic arthritis
  • CAPLYTA sNDA approved, relapse prevention in schizophrenia
  • TECVAYLI positive CHMP with daratumumab in r/r myeloma
  • ETHICON 4000 stapler CE mark, EU
Deals & capital
  • Firefly Bio acquired, degrader antibody conjugate platform USD 1B
  • MeiraGTx buys Janssen bota-vec, ophthalmic gene therapy USD 25M up, USD 75M total
  • DePuy Synthes licenses MinMaxMedical Gemtrack, musculoskeletal
  • CG Bio NOVOSIS co-promotion with DePuy Synthes
On the clock · next quarter
  • FDA decisionIMAAVY in wAIHA, no approved therapy exists today
  • ReadoutRYBREVANT FASPRO head and neck cancer
  • ReadoutERLEADA Ph3, prostate cancer surgery risk
  • CorporateOrthopaedics separation removes a USD 2.4B-a-quarter business
Free cash flow USD 8.7B six-month YTD, estimated 15 July, +40.0%/SG&A USD 6.43B, 25.4% of sales, +9.2%/Cost of sales USD 8.05B, 31.8%/Pre-tax earnings USD 6.75B, 26.7%/Net earnings USD 5.53B, -0.1%/Adjusted net earnings USD 7.08B, +5.7%
6.1%6.5%Adj op sales growth
USD 100.8BUSD 101.1BReported sales
USD 11.55USD 11.68Adjusted EPS
USD 1.17USD 1.15Euro rate assumption
Synopulse
The Top Line · Q2 2026
Q2 2026 release and supplementary sales data · extracted 20 August 2026
What decides the next twelve months Three things. Whether Immunology turns positive as TREMFYA compounds against a shrinking STELARA base. The Orthopaedics separation, which removes $2,418 million of quarterly revenue and changes what the remaining company looks like. And IMAAVY, now in Priority Review as a potential first-in-class treatment for warm autoimmune haemolytic anaemia, which is the nearest thing on the board to a new franchise rather than an extension of an old one.
03 Beat · Humira base shrinking

Skyrizi added more in one quarter than Humira has left to sell

Skyrizi reached $5,505 million, up 24.4 percent, which means it added roughly $1,080 million of revenue against the same quarter last year. Humira sold $756 million in the entire quarter. The successor is now adding more every three months than the predecessor has left to lose, and that is the cleanest statement of where AbbVie stands after the biggest patent cliff in the industry’s history.

Humira fell 35.9 percent and shed about $423 million. Immunology absorbed it and grew 15.1 percent to $8,786 million, with Rinvoq adding a further 24.5 percent to $2,525 million. Between them Skyrizi and Rinvoq are $8,030 million, which is 47.3 percent of everything AbbVie sold in the quarter and more than ten times what Humira now contributes.

Oncology is the exception, down 1.5 percent to $1,650 million as Imbruvica fell 29.4 percent to $532 million. AbbVie’s answer was to buy elsewhere: $10,900 million for Apogee Therapeutics in dermatology in June, an option over Kestrel Therapeutics worth up to $1,450 million in oncology, and a pain licence from Haisco. The Apogee price is more than fourteen times what Humira sold in the quarter.

Reported earnings tell a different story from adjusted. Diluted EPS was $2.03 against $0.52, but adjusted EPS was $3.65, up 22.9 percent. The gap is $1,689 million of intangible amortisation and $1,518 million from a change in fair value of contingent consideration, and the effective tax rate fell to 15.5 percent from 39.4 percent.

03Mkt cap AbbVie NYSE ABBV · Mkt cap USD 470B
Total revenue
USD 16.99B
+10.2%reported+9.5%operational
Revenue added
+USD 1.57B
From USD 15.42B, +10.2%
Profit margin
37.9%+614bp
Operating margin, from 31.7%
R&D expense
USD 2.34B+10.0%
13.8% of sales, unchanged
Adjusted EPS
USD 3.65+22.9%
Reported USD 2.03, from USD 0.52
Gross margin
74.7%+292bp
Gross profit USD 12.7B
Sales by region · as reported
USD 16.99B Q2 SALES
United StatesUSD 12.86B · +9.3%75.7%
InternationalUSD 4.13B · +12.8%24.3%
Therapy area · year on year, reported
ImmunologyUSD 8.79B+15.1%
NeuroscienceUSD 3.23B+20.3%
OncologyUSD 1.65B-1.5%
AestheticsUSD 1.28B+0.3%
The swing · year on year
Humira-USD 423M
Skyrizi+USD 1.08B
Skyrizi added USD 1.08B in the quarter, more than the USD 756M Humira has left to sell. Humira is down 35.9% and Immunology still grew 15.1%.
Top 5 · by revenue
SkyriziImmunologyUSD 5.5B+24.4%
RinvoqImmunologyUSD 2.52B+24.5%
VraylarNeuroscienceUSD 1.07B+18.9%
Botox TherapeuticNeuroscienceUSD 1.04B+12.2%
VenclextaOncologyUSD 771M+11.6%
Eroding and emerging
Humirabiosimilar hitUSD 756M-35.9%
ImbruvicaOncologyUSD 532M-29.4%
UbrelvyNeuroscienceUSD 392M+16.0%
QuliptaNeuroscienceUSD 350M+30.9%
VyalevNeuroscienceUSD 256M+100%
Deals & capital
  • Apogee Therapeutics acquired, dermatology USD 10.9B
  • Kestrel Therapeutics option to acquire, oncology USD 1.45B total
  • Haisco pain therapies licence USD 30M up, USD 745M total
  • Seoul National University Hospital research collaboration, oncology
Reported against adjusted
  • Intangible amortisation USD 1,689M, the largest reconciling item
  • Contingent consideration USD 1,518M from a change in fair value
  • Effective tax rate 15.5% against 39.4% a year ago
  • Diluted EPS USD 2.03 reported against USD 3.65 adjusted
On the clock · next quarter
  • WatchOncology down 1.5%, the only franchise going backwards
  • WatchImbruvica down 29.4% to USD 532M and still eroding
  • WatchApogee USD 10.9B spent in dermatology, not oncology
  • WatchHumira USD 756M left, below what Skyrizi adds in a quarter
SG&A USD 3.63B, 21.4% of sales, +11.7%/Cost of products sold USD 4.29B, 25.3%/Acquired IPR&D and milestones USD 291M from USD 823M/Operating earnings USD 6.43B, 37.9%, +31.4%/Interest expense net USD 679M/Other expense net USD 1.48B
Synopulse
The Top Line · Q2 2026
Q2 2026 results release · extracted 20 August 2026
What decides the next twelve months Whether Oncology stops falling. Immunology and Neuroscience are both compounding above 15 percent and Aesthetics is flat, so Oncology at minus 1.5 percent is the only franchise going backwards, and Imbruvica is still shrinking at 29.4 percent. AbbVie spent $10,900 million on Apogee in dermatology rather than oncology, which says the answer is not coming from the existing pipeline.
04 Sales +5% · pre-tax loss

Keytruda stopped growing and its own subcutaneous version covered the gap

Keytruda sold $7,904 million against $7,956 million a year earlier. The biggest medicine in the world went backwards, by 0.65 percent. What closed the gap was Keytruda Qlex, the subcutaneous formulation, which took $463 million from nothing a year ago. Together they are $8,367 million, up 5.2 percent, and 50.4 percent of everything Merck sold.

Three products that barely existed twelve months ago added $919 million between them: Qlex $463 million, Winrevair $252 million as it grew 75 percent to $588 million, and Ohtuvayre $204 million from zero. Merck added $801 million in total, so everything else in the portfolio net shrank by $118 million.

The erosion is concentrated and old. Januvia and Janumet fell 31 percent to $429 million combined, shedding $194 million. Lagevrio is effectively finished at $5 million against $83 million. Dificid fell 77 percent and Vaxneuvance 35 percent. Against that, Prevymis grew 29 percent, Welireg 67 percent and Capvaxive 43 percent.

The bottom line went the other way entirely. Merck recorded a pre-tax loss of USD 683M against income of USD 4,999M, and a net loss of USD 1,335M against earnings of USD 4,427M. Research and development was USD 9,741M against USD 4,048M, 58.7 percent of sales, because two acquisitions were booked straight to R&D as asset acquisitions: Terns at USD 5.7B this quarter and Cidara at USD 9.0B in the first, USD 13.8B across the half.

04Mkt cap Merck & Co NYSE MRK · Mkt cap USD 375.5B
Total revenue
USD 16.61B
+5%nominal+4%ex-fx
Revenue added
+USD 801M
From USD 15.81B, +5.1%
Profit margin
-4.1%-3,574bp
Pre-tax margin, from +31.6%
R&D expense
USD 9.74B+140.6%
58.7% of sales, from 25.6%
Diluted EPS
-USD 0.54-131%
From USD 1.76, GAAP
Gross margin
73.5%-397bp
Gross profit USD 12.21B
Sales by region · as reported
USD 14.76B PHARMA Q2
United StatesUSD 8.83B · +6.0%59.8%
EuropeUSD 2.8B · +9.8%19.0%
Latin AmericaUSD 636M · n/d4.3%
Asia-Pacific ex China, JapanUSD 636M · n/d4.3%
JapanUSD 558M · -7.5%3.8%
Other regionsUSD 1.3B · n/d8.8%
Segment and franchise · year on year
Pharmaceutical USD 14.76B +5.1%Animal Health USD 1.77B +7.8%
Keytruda + QlexOncologyUSD 8.37B+5.2%
Vaccinesselected brandsUSD 2.23B-2.1%
Animal HealthsegmentUSD 1.77B+7.8%
Infectious Diseasesselected brandsUSD 1.06B-1.6%
Cardiometabolic, Resp.selected brandsUSD 996M+81.5%
Other oncologyalliances and WeliregUSD 1.04B+16.4%
DiabetesJanuvia, JanumetUSD 429M-31.1%
The swing · year on year
The rest of the portfolio-USD 118M
Qlex, Winrevair, Ohtuvayre+USD 919M
Three launches added USD 919M against total company growth of USD 801M, so everything else net shrank USD 118M. Keytruda itself fell 0.65% to USD 7.9B.
Top 5 · by revenue
Keytrudabase formulationUSD 7.9B-0.7%
Gardasil / Gardasil 9VaccinesUSD 1.17B+3.8%
ProQuad, M-M-R II, VarivaxVaccinesUSD 592M-2.8%
WinrevairCardiometabolicUSD 588M+75.0%
BridionInfectious DiseasesUSD 497M+7.8%
Launching and eroding
Keytruda Qlexsubcutaneous, from zeroUSD 463Mnew
Ohtuvayrefrom zeroUSD 204Mnew
WeliregOncologyUSD 271M+67.3%
Januvia + JanumetDiabetesUSD 429M-31.1%
Lagevriofrom USD 83MUSD 5M-94.0%
Cleared this quarter
  • LIPFENDRA FDA approval, first and only oral PCSK9 inhibitor
  • KEYTRUDA and QLEX FDA approval with WELIREG in adjuvant clear cell renal cell carcinoma
  • KEYTRUDA and QLEX FDA approval with Trodelvy in first-line PD-L1 positive TNBC
  • calderasib FDA Breakthrough Therapy designation, KRAS G12C with KEYTRUDA
Deals & capital
  • Protillion Biosciences development and commercialisation deal USD 510M total
  • Adcendo ApS clinical trial agreement
  • Exelixis clinical trial agreement, zanzalintinib
  • Degron Therapeutics research partnership, molecular glue degraders
On the clock · next quarter
  • PDUFAifinatamab deruxtecan under FDA review, decision date 10 October 2026, with Daiichi Sankyo
  • Readoutsac-TMT positive topline in advanced or recurrent endometrial cancer
  • Readouttulisokibart positive topline, Phase 3 ATLAS-UC induction study
  • WatchKeytruda Qlex conversion rate ahead of the 2028 base patent expiry
Cost of sales USD 4.4B, 26.5% of sales/SG&A USD 2.9B, 17.5% of sales/Restructuring USD 151M from USD 560M/Total costs and expenses USD 17.29B against revenue of USD 16.61B/Income tax provision USD 654M on a pre-tax loss/H1 net loss -USD 5.58B, H1 R&D USD 22.33B
Synopulse
The Top Line · Q2 2026
Q2 2026 results release Table 3 and results presentation · extracted 20 August 2026
What decides the next twelve months Whether the charges stop. Merck expensed USD 13.8 billion of acquired research through the income statement in six months, turning a business that grew sales 5 percent into a pre-tax loss, and the Keytruda succession problem it is buying against has not moved: the base product is flat and Qlex is at USD 463 million. The company is paying now, in reported earnings, for pipeline that arrives after 2028.
05 CER +6% · reported -2%

The Swiss franc took away more than the business added

Roche’s underlying business grew 6 percent at constant exchange rates, worth about CHF 1,857 million. Currency cost it CHF 2,437 million. Reported sales therefore fell 2 percent to CHF 30,364 million while the same half, measured in dollars, grew 8 percent. Every headline on this card moves in opposite directions depending on which currency you read it in.

The pattern repeats down the statement. Core operating profit rose 10 percent at CER and fell 1 percent in francs to CHF 11,856 million. Core earnings per share rose 9 percent at CER and fell 2 percent in francs to CHF 10.85. IFRS operating profit rose 6 percent at CER and fell 6 percent in francs. The business improved its core operating margin to 39.0 percent from 38.8 percent and still reported lower profit.

Cash conversion is where the improvement shows without translation noise. Free cash flow rose 26 percent in francs to CHF 4,197 million, and 58 percent at constant rates, taking it from 10.7 percent of sales to 13.8 percent. Research and development fell 5 percent to CHF 5,765 million, or 19.0 percent of sales from 19.6 percent.

Pharmaceuticals grew 6.2 percent at CER to CHF 23,629 million with a core operating margin of 53.0 percent. Diagnostics grew 3.4 percent to CHF 6,735 million but its margin fell to 17.5 percent from 18.0 percent, held back by Near Patient Care, down 5 percent, and Asia-Pacific, down 5 percent. Net debt rose 37 percent to CHF 22,071 million.

05Mkt cap Roche SIX ROG · Mkt cap USD 372.55B
Total revenue
CHF 30.36B
-2%francs+6%CER
Revenue added
-CHF 580M-1.9%
From CHF 30.94B, +6% at CER
Profit margin
39.0%+20bp
Core operating margin, half year
R&D expense
CHF 5.76B-5%
19.0% of sales, +1% at CER
Core EPS
CHF 10.85-2%
IFRS diluted CHF 8.52, +9% at CER
Gross margin
85.65%
Sales less cost of sales, half year
Sales by region · as reported
CHF 23.63B PHARMA H1
United StatesCHF 12.23B · +6% CER51.8%
InternationalCHF 5.52B · +10% CER23.4%
EuropeCHF 4.52B · +1% CER19.1%
JapanCHF 1.36B · +11% CER5.8%
Division and customer area · CER growth
Pharmaceuticals CHF 23.63B +6% CERDiagnostics CHF 6.74B +3% CER
Pharmaceuticals53.0% core marginCHF 23.63B+6%
Diagnostics17.5% core marginCHF 6.74B+3%
Core Labin DiagnosticsCHF 3.76B+4%
Molecular Labin DiagnosticsCHF 1.2B+3%
Near Patient Carein DiagnosticsCHF 909M-5%
Pathology Labin DiagnosticsCHF 874M+11%
The swing · half on half
Currency-CHF 2.44B
Underlying growth at CER+CHF 1.86B
The business added CHF 1.86B at constant rates and the franc removed CHF 2.44B. Reported sales fell CHF 580M. In US dollars the same half grew 8 percent.
Top 5 · H1 sales, CER growth
Ocrevusmultiple sclerosisCHF 3.47B+7%
Hemlibrahaemophilia ACHF 2.49B+11%
Vabysmoeye diseasesCHF 2.06B+8%
TecentriqimmunotherapyCHF 1.7B+6%
Xolairchronic hives, food allergyCHF 1.67B+27%
Eroding and emerging
Perjetabreast cancerCHF 1.39B-7%
Actemra / RoActemrarheumatoid arthritisCHF 1.07B-9%
Herceptinbreast, gastricCHF 462M-12%
Avastinvarious cancersCHF 414M-15%
Columviblood cancerCHF 196M+70%
Divisions · core operating margin
  • Pharmaceuticals 53.0% against 52.2%, sales up 6.2% at CER
  • Diagnostics 17.5% against 18.0%, sales up 3.4% at CER
  • Group 39.0% against 38.8%, sales up 5.6% at CER
  • Net debt CHF 22.07B against CHF 16.16B at December, up 37%
Diagnostics by region
  • Europe, Middle East, Africa CHF 2.47B, 36.6% of the division, up 3% at CER
  • North America CHF 2.21B, 32.8%, up 8% at CER
  • Asia-Pacific CHF 1.52B, 22.6%, down 5% at CER
  • Latin America CHF 536M, 8.0%, up 10% at CER
On the clock · second half
  • WatchThe franc an 8 point gap between CER and reported growth
  • WatchNear Patient Care down 5% at CER, the only shrinking Diagnostics area
  • WatchNet debt up 37% to CHF 22.07B in six months
  • WatchPharma growth 6.2% at CER against 9.6% in the same half last year
Reported in Swiss francs · half year, not quarter/IFRS operating profit CHF 9.67B, 31.9% of sales from 33.4%/Net income CHF 7.33B, -6% in francs, +6% at CER/Net income to shareholders CHF 6.87B/IFRS diluted EPS CHF 8.52 from CHF 9.23/Operating free cash flow CHF 6.26B, 20.6% of sales
Synopulse
The Top Line · Q2 2026
Half-Year Report 2026, key interim results · extracted 20 August 2026
What decides the next twelve months Whether the franc keeps deciding the headline. Roche improved its core operating margin, grew free cash flow 26 percent in its own currency and still reported falling sales and earnings, which is a translation problem rather than a trading one. The real question underneath is Pharmaceuticals growth at 6.2 percent at CER against 9.6 percent in the same half last year, and a Diagnostics margin that slipped while every peer in this edition was expanding theirs.
06 Sales up · net income down 19%

Oncology added $1,162 million and Entresto took away $1,176 million

Entresto lost more than half its revenue in a quarter, falling 50 percent to $1,181 million from $2,357 million. That is $1,176 million gone from a single brand, and it dragged the whole cardiovascular, renal and metabolic area down 36 percent to $1,688 million.

Oncology grew 35 percent to $4,515 million and added $1,162 million. Put the two side by side and the quarter explains itself: the biggest engine grew by $14 million less than the biggest loss took away. Net sales rose 1 percent at constant currency and 3 percent as reported, which is the whole story in one line.

Underneath, the compounding is real. Kisqali reached $1,695 million, up 44 percent, Kesimpta $1,424 million, up 32 percent, and Scemblix $562 million, up 89 percent. Cosentyx is still the largest brand at $1,824 million. What Novartis does not yet have is one of these at Entresto’s old scale.

Profit fell much harder than sales. Net income dropped 19 percent to $3,257 million while sales rose, and the two reasons are below the operating line: interest expense went from $289 million to $462 million, and the effective tax rate went from 11.2 percent to 23.7 percent. Core earnings per share, which strips those out, was flat at $2.41.

06Mkt cap Novartis NYSE NVS · Mkt cap USD 304.7B
Total revenue
USD 14.41B
+3%reported+1%const fx
Revenue added
+USD 354M
From USD 14.05B, +1% at CER
Profit margin
33.0%-160bp
Operating margin, core 41.2%
R&D expense
USD 2.85B+4.4%
19.8% of sales, from 19.4%
Core EPS
USD 2.41-0.4%
Reported USD 1.71, from USD 2.07
Gross margin
78.0%-391bp
Gross profit USD 11.24B
Sales by region · as reported
USD 14.41B Q2 SALES
Rest of worldUSD 8.45B · +8.5% derived58.7%
United StatesUSD 5.95B · -5.2% derived41.3%
Therapy area · year on year, reported
OncologyUSD 4.51B+35%
Established brandsUSD 3.55B-12%
ImmunologyUSD 2.78B+9%
NeuroscienceUSD 1.88B+29%
Cardio, renal, metabolicUSD 1.69B-36%
The swing · year on year
Entresto-USD 1.18B
Oncology franchise+USD 1.16B
The largest engine grew by USD 14M less than the largest loss took away. Entresto is down 50% and Oncology is up 35%, and net sales still moved only 1% at constant currency.
Top 5 · by revenue
CosentyxImmunologyUSD 1.82B+12%
KisqaliOncologyUSD 1.7B+44%
KesimptaNeuroscienceUSD 1.42B+32%
Entrestogeneric erosionUSD 1.18B-50%
PluvictoOncologyUSD 651M+43%
Compounding and eroding
ScemblixOncologyUSD 562M+89%
LeqvioCardiovascularUSD 480M+61%
XolairImmunologyUSD 342M-23%
FabhaltaOncologyUSD 225M+88%
TasignaestablishedUSD 142M-57%
Cleared this quarter
  • Cosentyx FDA approval, juvenile ankylosing spondylitis
  • Fabhalta FDA approval, IgA nephropathy
  • Itvisma EU approval, intrathecal onasemnogene for spinal muscular atrophy
  • Rhapsido EU and Japan approval, chronic spontaneous urticaria
Deals & capital
  • Antares Therapeutics research partnership with licence option, oncology USD 105M up, USD 1.91B total
  • Orionis Biosciences development and commercialisation licence USD 40M up, USD 1.44B total
On the clock · awaiting decision
  • SubmissionKPE179 del-zota, accelerated approval filing in Duchenne muscular dystrophy
  • DecisionPluvicto metastatic hormone-sensitive prostate cancer, US and Japan
  • DecisionVAY736 ianalumab in Sjögren’s disease, US, EU and Japan
  • DecisionCosentyx polymyalgia rheumatica, US, EU and Japan
Free cash flow USD 5.56B from USD 6.33B, -12.2%/SG&A USD 3.24B, 22.5% of sales, down 5.8%/Cost of goods sold USD 3.71B, 25.8%/Other revenues USD 543M/Operating income USD 4.75B, 33.0%, -2%/Core operating income USD 5.94B, 41.2%, flat
Synopulse
The Top Line · Q2 2026
Q2 2026 interim report and results presentation · extracted 20 August 2026
What decides the next twelve months Whether anything reaches Entresto’s old scale. Kisqali at $1,695 million is the closest and is growing 44 percent, but Entresto was $2,357 million a year ago and is now $1,181 million, so the gap is still wider than any single replacement. Below that, the tax rate more than doubled to 23.7 percent and interest expense rose 60 percent, and neither is a trading problem that better selling fixes.
07 Core +21% · reported profit down

Oncology added more revenue than the whole company did

AstraZeneca added $871 million of revenue in the quarter. Oncology on its own added $1,011 million, growing 16 percent to $7,327 million. The arithmetic only closes one way: everything outside Oncology shrank by $140 million, and Oncology is now 48 percent of the company.

The drag is named and known. Cardiovascular, Renal and Metabolism fell 15 percent to $2,772 million as Farxiga lost US exclusivity, shedding about $489 million. China fell 7 percent to $1,587 million under volume-based procurement, and 13 percent at constant currency. Against that, Respiratory and Immunology grew 13 percent and Rare Disease 9 percent.

The gap between reported and core is the widest in this edition. Reported operating profit fell 10 percent to $3,164 million and reported operating margin dropped 4 points to 21 percent. Core operating profit rose 12 percent to $5,158 million with the margin up 2 points to 34 percent. Thirteen points separate the two margins, and reported EPS of $1.61 sits against core EPS of $2.63.

The pipeline delivered and disappointed in the same quarter. Imfinzi met its primary endpoint in VOLGA and NILE and missed in EMERALD-2. Wainua missed in CARDIO-TTRansform in ATTR-CM, and Ultomiris missed in HSCT-TMA. On the other side, Baxfendy took a first US approval in hypertension and Enhertu cleared three separate label expansions.

07Mkt cap AstraZeneca NASDAQ AZN · Mkt cap USD 255.24B
Total revenue
USD 15.38B
+6%reported+5%const fx
Revenue added
+USD 871M
From USD 14.51B, Oncology alone +USD 1.01B
Profit margin
34%+2pp
Core operating margin, reported 21%
R&D expense
USD 4.05B+14%
26.3% of revenue, core 24%
Core EPS
USD 2.63+21%
Reported USD 1.61, +2%
Gross margin
84%+1pp
Reported and core alike
Sales by region · as reported
USD 15.38B Q2 REVENUE
United StatesUSD 6.69B · +6%43.5%
Emerging MarketsUSD 3.92B · +4%25.5%
EuropeUSD 3.42B · +11%22.2%
Established RoWUSD 1.36B · +4%8.8%
Therapy area · year on year, reported
OncologyUSD 7.33B+16%
BioPharmaceuticalsUSD 5.33B-5%
Cardio, renal, metabolicin BioPharmaUSD 2.77B-15%
Respiratory, immunologyin BioPharmaUSD 2.43B+13%
Rare DiseaseUSD 2.49B+9%
Other MedicinesUSD 233M-7%
The swing · year on year
Cardio, renal, metabolic-USD 489M
Oncology+USD 1.01B
Oncology added USD 1.01B against total company growth of USD 871M. Everything outside Oncology shrank USD 140M, with Farxiga losing US exclusivity and China down 13% at constant currency.
Phase III read outs · met
Imfinzi VOLGAMIBC, non-cisplatinMet
Imfinzi NILE1L bladderMet
sone-ve CLARITY-Gastric012L+ Cldn18.2+ gastricMet
Ultomiris MG-319gMG paediatricMet
Phase III read outs · missed
Wainua CARDIO-TTRansformATTR-CMMissed
Imfinzi EMERALD-2adjuvant HCCMissed
Ultomiris TMA-313HSCT-TMA adultsMissed
Cleared this quarter
  • Baxfendy first US approval, hypertension, BaxHTN
  • Enhertu three US and EU expansions across HER2+ breast and solid tumours
  • Truqap US approval, PTEN-deficient mHSPC
  • Fasenra hypereosinophilic syndrome, US, EU, Japan and China
Deals & capital
  • Nucs AI research partnership, AI-driven imaging in oncology
  • Owkin contract service agreement
  • YMCA contract service agreement, oncology
On the clock · filed or accepted
  • Filedtozorakimab COPD, EU and China
  • FiledUltomiris IgA nephropathy, US and Japan
  • FiledBaxfendy hypertension, Japan
  • Filedefzimfotase alfa hypophosphatasia, Japan
SG&A USD 5.65B, 36.7% of revenue, +16%, core USD 4.05B at 26%/Core R&D USD 3.66B, +6%/Alliance revenue USD 874M, +34%/Operating profit USD 3.16B, 21% margin, -10%/Core operating profit USD 5.16B, 34% margin, +12%/Net finance expense USD 355M
Synopulse
The Top Line · Q2 2026
H1 and Q2 2026 results announcement, 27 July 2026 · extracted 20 August 2026
What decides the next twelve months Concentration. Oncology at 48 percent of revenue is carrying a company whose other half is flat to shrinking, and the two things that could change that both went the wrong way this quarter: CARDIO-TTRansform missed in ATTR-CM and EMERALD-2 missed in adjuvant liver cancer. Baxfendy’s first US approval in hypertension is the nearest thing to a new non-oncology leg, and it is starting from zero.
08 Beat · costs held flat

Revenue rose $875 million and operating costs rose $17 million

Amgen added $875 million of revenue in the quarter and $17 million of operating cost. Total operating expenses were $6,540 million against $6,523 million a year earlier, which means 98 percent of the revenue increase fell straight to operating income. Operating income rose $858 million to $3,514 million.

Cost of sales did the work. It fell to $2,811 million from $3,011 million even as product sales grew 8.7 percent, taking gross margin to 72.0 percent from 67.2 percent, a gain of 484 basis points. Research and development still rose 7.1 percent to $1,868 million, so the saving is manufacturing and mix rather than restraint on the pipeline.

Six products carry roughly 70 percent of product sales and all six are compounding: Tezspire up 42 percent, Evenity 38 percent, Repatha 37 percent, biosimilars 29 percent, rare disease 21 percent and innovative oncology 18 percent. Amgen also disclosed free cash flow of $3.5 billion and capital expenditure of $0.5 billion.

Reported and adjusted earnings moved in opposite directions, and the reported number is the flattering one for once. GAAP diluted EPS was $4.37 against $2.65, up 65 percent, while non-GAAP EPS rose 4 percent to $6.29. Prior-year GAAP was held down by $394 million of other expense and a tax rate of 8.7 percent; this quarter the tax rate was 14.2 percent.

08Mkt cap Amgen NASDAQ AMGN · Mkt cap USD 238.74B
Total revenue
USD 10.05B
+9.5%reported+8.7%products
Revenue added
+USD 875M
From USD 9.18B, opex added only USD 17M
Profit margin
48.4%-50bp
Non-GAAP operating margin
R&D expense
USD 1.87B+7.1%
18.6% of revenue, non-GAAP USD 1.85B
Non-GAAP EPS
USD 6.29+4%
Reported USD 4.37, from USD 2.65
Gross margin
72.0%+484bp
Cost of sales down to USD 2.81B
The swing · year on year
Operating costs added+USD 17M
Revenue added+USD 875M
Total operating expenses moved USD 17M against revenue up USD 875M, so 98% of the increase reached operating income. Cost of sales actually fell USD 200M.
Six growth drivers · ~70% of product sales
TezspireInflammation+42%
EvenityGeneral Medicine+38%
RepathaGeneral Medicine+37%
Biosimilarsportfolio+29%
Rare Diseasefranchise+21%
Innovative Oncologyfranchise+18%
Cost structure · non-GAAP, % of product sales
Cost of salesfrom 17.7%19.6%
R&Dfrom 19.2%19.4%
SG&Afrom 18.8%18.0%
Operating incomefrom 48.9%48.4%
Tax ratefrom 14.2%15.6%
Cleared this quarter
  • Uplizna EU approval, generalised myasthenia gravis
  • Imdelltra approvals and label updates in EU, China and Japan
  • Repatha positive CHMP opinion, primary prevention
  • Imdelltra EU approval, second-line extensive-stage small cell lung cancer
Deals & capital
  • Zai Lab clinical trial agreement, zocilurtatug pelitecan in oncology
  • Free cash flow USD 3.5B in the quarter against USD 0.5B of capital expenditure
On the clock · 2026 milestones
  • Phase 3MariTide three type 2 diabetes studies plus switching and maintenance extensions
  • Phase 3Uplizna chronic inflammatory demyelinating polyneuropathy, H2 2026 to H1 2027
  • CompletionDazodalibep two Phase 3 Sjögren’s disease studies, H2
  • CompletionTezspire Phase 3 eosinophilic oesophagitis, H2
Free cash flow USD 3.5B and CapEx USD 500M in the quarter, both non-GAAP/SG&A USD 1.75B, +3.2%, non-GAAP USD 1.72B at 18.0% of product sales/Product sales USD 9.54B, +8.7%/Other revenues USD 517M/Operating income USD 3.51B, +32.3%, non-GAAP USD 4.61B at 48.4% of product sales/Interest expense net USD 673M
Synopulse
The Top Line · Q2 2026
Q2 2026 results presentation and GAAP reconciliation · extracted 20 August 2026
What decides the next twelve months Whether the cost line stays still. A quarter where revenue rises $875 million and costs rise $17 million is not repeatable indefinitely, and non-GAAP operating margin actually slipped to 48.4 percent of product sales from 48.9 percent, so the adjusted picture is flat rather than expanding. MariTide is the swing factor: three Phase 3 diabetes studies plus switching and maintenance work, and it is the only asset on the board that could change the size of the company.
09 Sales +2% · profit -19%

Sales rose 1.6 billion kroner and research spending rose 6.1 billion

Novo Nordisk added DKK 1,631 million of sales in the quarter and DKK 6,097 million of research and development. R&D rose 52 percent to DKK 17,787 million, which is 3.7 times the increase in sales, and took research to 22.7 percent of revenue from 15.2 percent.

Cost of goods sold moved the same way, up 33 percent to DKK 17,100 million against sales up 2 percent. Gross margin fell 507 basis points to 78.2 percent. Operating profit dropped 19 percent to DKK 27,061 million and the operating margin fell from 43.5 percent to 34.5 percent. Net profit fell 21 percent and diluted earnings per share went from DKK 5.96 to DKK 4.75.

The Rare disease segment turned loss-making. Sales were flat at DKK 4,907 million and it recorded an operating loss of DKK 1,295 million against a profit of DKK 518 million a year earlier, a margin of minus 26.4 percent. Obesity and Diabetes care grew 2.3 percent to DKK 73,581 million with its own operating margin down from 45.8 percent to 38.5 percent.

Commercially the launches are landing. US Wegovy weekly prescriptions are around 575,000 with the oral pill at roughly 265,000, the pill is now approved in the EU, UK and UAE, and Wegovy 7.2 mg launched in the UK. Novo holds a 58 percent GLP-1 volume share. Full-year adjusted guidance was still raised, to a range of 0 to minus 6 percent sales growth at constant currency.

09Mkt cap Novo Nordisk NYSE NVO · CPH NOVO-B · Mkt cap USD 205.53B
Total revenue
DKK 78.49B
+2.1%reported+7%adj CER
Revenue added
+DKK 1.63B
From DKK 76.86B, R&D added DKK 6.1B
Profit margin
34.5%-900bp
Operating margin, from 43.5%
R&D expense
DKK 17.79B+52.2%
22.7% of sales, from 15.2%
Diluted EPS
DKK 4.75-20.3%
From DKK 5.96, basic DKK 4.74
Gross margin
78.2%-507bp
Gross profit DKK 61.39B
Segment · year on year, reported
Obesity and Diabetes DKK 73.58B +2.3%Rare disease DKK 4.91B -0.2%
Obesity and Diabetes38.5% op marginDKK 73.58B+2.3%
Rare disease-26.4% op marginDKK 4.91B-0.2%
The swing · year on year
R&D added+DKK 6.1B
Sales added+DKK 1.63B
Research spending grew by 3.7 times the growth in sales. Add cost of goods sold, up DKK 4.25B, and the two cost lines together rose DKK 10.35B against DKK 1.63B of new revenue.
Income statement · DKK million
Net salesfrom 76,857DKK 78.49B+2.1%
Gross profitfrom 64,011DKK 61.39B-4.1%
Operating profitfrom 33,449DKK 27.06B-19.1%
Profit before taxfrom 33,805DKK 26.88B-20.5%
Net profitfrom 26,503DKK 20.99B-20.8%
Cost lines · % of sales
Research and developmentfrom 15.2%22.7%
Cost of goods soldfrom 16.7%21.8%
Sales and distributionfrom 22.8%19.1%
Administrativefrom 1.7%1.7%
Operating marginfrom 43.5%34.5%
Cleared this quarter
  • Wegovy 7.2 mg approved in the US, UK and EU, launched in the UK
  • Wegovy pill approved in the UAE, UK and EU, launched in the UK and UAE
  • Ozempic 2.0 mg launched in around ten countries
  • Ten approvals more than ten regulatory approvals in the half
Deals & capital
  • Cellu development and commercialisation deal
  • OpenAI contract service agreement
  • Shantha Biologics contract service agreement
  • H1 capital DKK 24.84B invested and DKK 35.31B paid in dividends
On the clock · next quarter
  • GuidanceFull year adjusted sales growth of 0 to -6% at constant currency against +7% in the half
  • ReadoutEtavopivat Phase 3 HIBISCUS successfully completed
  • WatchRare disease operating loss of DKK 1.29B, first negative margin on the card
CapEx DKK 24.84B in the half, plant DKK 23.99B and intangibles DKK 854M/Reported in Danish kroner/Sales and distribution DKK 15B, down 14.5%/Administrative DKK 1.31B/Financial income DKK 1.31B from DKK 5.31B/Income taxes DKK 5.89B, effective rate 21.9% from 21.6%
Synopulse
The Top Line · Q2 2026
Q2 2026 condensed interim financial statements · extracted 20 August 2026
What decides the next twelve months The gap between the half and the year. Adjusted sales grew 7 percent at constant currency in the half and full-year guidance is 0 to minus 6 percent, which implies a sharply negative second half on the company’s own numbers. Underneath that, R&D at 22.7 percent of sales and gross margin down 507 basis points have already cut the operating margin by nine points, and Rare disease is now losing money. Wegovy volume is not the problem; what it costs to make and defend is.
10 Sales +13% · net earnings -48%

Two thirds of the growth is a company Abbott did not own a year ago

Abbott’s reported revenue grew 13.0 percent. On a comparable basis it grew 4.8 percent. The 8.2 point gap is one line: Cancer Diagnostics contributed $919 million in the quarter and did not exist inside Abbott a year ago. Exact Sciences closed on 23 March 2026.

Of the $1,451 million Abbott added against the prior year, $919 million came from the acquisition and $532 million from everything it already owned. US Diagnostics grew 104.8 percent as reported and 4.0 percent on a comparable basis, which is the same arithmetic at segment level.

The rest of the portfolio is doing what it has been doing. Medical Devices grew 9.0 percent to $5,853 million and 8.4 percent comparable, the largest segment and the most consistent. Established Pharmaceuticals grew 8.4 percent to $1,499 million, entirely international. Nutrition is the only segment going backwards, down 3.1 percent to $2,144 million with US nutrition off 9.0 percent.

Earnings went the opposite way from sales. Operating earnings fell 17.5 percent to USD 1,693M and net earnings fell 47.8 percent to USD 928M. Three lines did it: selling and administrative costs rose USD 934M, intangible amortisation USD 238M, and interest expense USD 230M on the USD 19.8B of debt raised to buy Exact Sciences. Diluted EPS was USD 0.53 against USD 1.01.

10Mkt cap Abbott NYSE ABT · Mkt cap USD 199.31B
Total revenue
USD 12.59B
+13.0%reported+4.8%comparable
Revenue added
+USD 1.45B
From USD 11.14B, USD 919M of it acquired
Profit margin
13.4%-497bp
Operating margin, from 18.4%
R&D expense
USD 892M+23%
7.1% of sales, from 6.5%
Diluted EPS
USD 0.53-47.5%
From USD 1.01, GAAP
Gross margin
57.7%+129bp
Excludes intangible amortisation
Sales by region · as reported
USD 12.59B Q2 SALES
InternationalUSD 7.38B · +7.5%58.6%
United StatesUSD 5.22B · +22.0%41.4%
Segment · reported growth, year on year
Medical DevicesUSD 5.85B+9.0%
DiagnosticsUSD 3.09B+42.3%
NutritionUSD 2.14B-3.1%
Est. PharmaceuticalsUSD 1.5B+8.4%
Structural Heartin Med DevicesUSD 597M+2.7%
The swing · year on year
Nutrition-USD 69M
Cancer Diagnostics+USD 919M
Cancer Diagnostics is USD 919M of revenue that was not inside Abbott a year ago. Of USD 1.45B added in total, the acquisition is USD 919M and the legacy business USD 532M.
Diagnostics · three ways
Core LaboratoryreportedUSD 1.42B+4.4%
Cancer DiagnosticsExact SciencesUSD 919M+13.3%
Rapid and Molecularrespiratory testing downUSD 755M-7.3%
Diagnostics totalcomparable +2.9%USD 3.09B+42.3%
Reported against comparable
Total companycomparable +4.8%+13.0%
UScomparable +3.5%+22.0%
Internationalcomparable +5.8%+7.5%
Diagnosticscomparable +2.9%+42.3%
Medical Devicescomparable +8.4%+9.0%
What changed the base
  • Exact Sciences acquisition closed 23 March 2026, now reported as Cancer Diagnostics
  • Rapid Diagnostics aggregated with Molecular and Point of Care into one business in 2026
  • Amplatzer Amulet moved from Structural Heart to Electrophysiology on 1 January 2026
  • Multi-year agreement final Structural Heart compensation payment recognised in Q1 2026
Deals & capital
  • ALZpath development and commercialisation licence, in vitro diagnostics
  • Exact Sciences contributed USD 919M of Q2 revenue in its first full quarter
On the clock · next quarter
  • Base effectQ1 2027 first quarter where Exact Sciences sits in both years and the gap closes
  • WatchNutrition US down 9.0%, the only segment shrinking
  • WatchRapid and Molecular down 8.0% comparable on respiratory virus testing
Cost of products sold USD 5.33B, excludes amortisation/Intangible amortisation USD 658M from USD 420M/SG&A USD 4.03B from USD 3.09B, +30.2%/Interest expense USD 351M from USD 121M/Earnings before taxes USD 1.52B from USD 2.15B/Diluted shares 1,743M
Synopulse
The Top Line · Q2 2026
Q2 2026 results release and non-GAAP revenue reconciliation · extracted 20 August 2026
What decides the next twelve months The base effect. Reported growth of 13.0 percent against comparable growth of 4.8 percent is a one-year phenomenon, and from Q1 2027 Exact Sciences sits in both years and the two numbers converge on the lower one. What has to carry the company after that is Medical Devices at 8.4 percent comparable, because Nutrition is shrinking and Rapid and Molecular Diagnostics is down 8.0 percent comparable on respiratory testing.
11 Operating loss · USD 11.18B charge

The charge was larger than the quarter’s entire revenue

Gilead booked $11,183 million of acquired in-process research and development in a quarter that produced $7,803 million of revenue. Add $1,750 million of IPR&D impairments and the two lines together come to $12,933 million, which is 1.7 times everything the company sold. Total costs and expenses were $18,197 million against $4,608 million a year earlier.

The result is an operating loss of $10,394 million against operating income of $2,474 million, and an operating margin of minus 133.2 percent against plus 34.9 percent. Diluted loss per share was $8.45 against earnings of $1.56. The effective tax rate was minus 2.4 percent.

The trading business underneath is fine and rather dull by comparison. Product sales grew 8 percent to $7,627 million, and excluding Veklury they grew 10 percent to $7,604 million. HIV rose 12 percent to $5,693 million and is now 74.6 percent of product sales. Liver Disease grew 10 percent, Oncology 3 percent, and product gross margin improved 60 basis points to 79.3 percent.

The deal sheet does not fully account for the charge. Gilead acquired Tubulis on 7 April for $3,150 million upfront against $5,000 million total, and the remaining transactions on the sheet are contract service agreements with Tempus, Orsini, Yuhan and the WHO. What sits behind the balance of the $11,183 million is not in the extracted material.

11Mkt cap Gilead Sciences NASDAQ GILD · Mkt cap USD 183B
Total revenue
USD 7.8B
+10%revenue+8%products
Revenue added
+USD 721M
From USD 7.08B, +10.2%
Profit margin
-133.2%
Operating margin, from +34.9%
R&D expense
USD 1.76B+18.3%
22.6% of revenue, from 21.1%
Diluted EPS
-USD 8.45-642%
From USD 1.56, on the IPR&D charge
Gross margin
79.3%+60bp
Product gross margin
Therapy area · year on year
HIVUSD 5.69B+12%
Liver DiseaseUSD 877M+10%
OncologyUSD 873M+3%
OtherUSD 161M-20%
VekluryUSD 23M-81%
The quarter · charge against revenue
IPR&D charge and impairments-USD 12.93B
Total revenue+USD 7.8B
Acquired IPR&D of USD 11.18B and impairments of USD 1.75B against USD 7.8B of revenue. Operating margin was -133.2% against +34.9% a year ago.
The charge · year on year
Acquired IPR&Dfrom USD 61MUSD 11.18B
IPR&D impairmentsfrom USD 190MUSD 1.75B
Total costs and expensesfrom USD 4.61BUSD 18.2B
Operating lossfrom +USD 2.47B-USD 10.39B
Net lossfrom +USD 1.96B-USD 10.5B
Ratios · % of revenue
Product gross marginfrom 78.7%79.3%
R&Dfrom 21.1%22.6%
SG&Afrom 19.3%24.6%
Operating marginfrom 34.9%-133.2%
Effective tax ratefrom 19.3%-2.4%
Deals & capital
  • Tubulis acquired 7 April, antibody drug conjugates USD 3.15B up, USD 5B total
  • Yuhan contract service agreement USD 139.8M
  • Tempus contract service agreement
  • Kite and Cencora contract service agreement
What the trading business did
  • HIV up 12% to USD 5.69B, now 74.6% of product sales
  • Product sales ex-Veklury up 10% to USD 7.6B
  • Veklury down 81% to USD 23M, effectively finished
  • Dividend declared USD 0.82 a share against USD 0.79
On the clock · next quarter
  • WatchThe charge whether more acquired IPR&D follows or this was a single event
  • WatchSG&A up to 24.6% of revenue from 19.3%, the sharpest cost move on the card
  • WatchOncology up only 3%, the slowest of the three named areas
Product sales USD 7.63B, +8%/Royalty and other revenue USD 176M from USD 27M/Cost of goods sold USD 1.58B/SG&A USD 1.92B, +40.7%, 24.6% of revenue/Interest expense USD 247M/Other income net USD 387M
Synopulse
The Top Line · Q2 2026
Q2 2026 condensed consolidated statements of operations · extracted 20 August 2026
What decides the next twelve months Whether this was one event. An $11.2 billion acquired IPR&D charge does not repeat, and the trading business under it grew product sales 8 percent with gross margin up 60 basis points, so on the operating line Gilead is intact. Two things to watch instead: SG&A rose to 24.6 percent of revenue from 19.3 percent, which is a permanent cost step rather than a one-off, and HIV at 74.6 percent of product sales leaves the company dependent on a single franchise that Oncology, up 3 percent, is not yet diversifying.
12 Reported loss · adjusted EPS flat

Every dollar of revenue growth came from alliances and royalties

Pfizer’s revenue rose 3 percent to $15,034 million, and its product revenues fell 1 percent to $11,863 million. The $381 million the company added came from alliance revenues, up 19 percent to $2,697 million, and royalties, up 11 percent to $474 million. On the medicines it sells itself, Pfizer went backwards by $91 million.

Below the operating line the quarter turned. Other income and deductions net was $3,716 million against $739 million a year earlier, an increase of $2,977 million, which is nearly eight times the $381 million of revenue Pfizer added. Restructuring and acquisition costs added a further $457 million against a $18 million credit last year.

The result is a reported net loss of $248 million against net income of $2,910 million, and a loss per share of $0.04 against earnings of $0.51. Adjusted income was flat at $4,440 million and adjusted diluted EPS flat at $0.77. The effective tax rate on reported results was 62.4 percent against 4.6 percent.

Spending went the other way from sales. Research and development rose 13 percent to $2,809 million, taking R&D to 18.7 percent of revenue from 16.9 percent, while selling and administrative costs were held flat at $3,411 million. Pfizer also signed a development and commercialisation licence with Innovent Biologics worth $650 million upfront against $10,500 million in total.

12Mkt cap Pfizer NYSE PFE · Mkt cap USD 160.96B
Total revenue
USD 15.03B
+3%reported+1%operational
Revenue added
+USD 381M
From USD 14.65B, alliances +USD 424M
Profit margin
-4.3%-2,511bp
Pre-tax margin, from +20.8%
R&D expense
USD 2.81B+13%
18.7% of revenue, from 16.9%
Adjusted EPS
USD 0.770%
Reported -USD 0.04, from USD 0.51
Gross margin
72.8%-144bp
Cost of sales 27.2% of revenue
Business · year on year, reported
Global BiopharmaUSD 14.66B+2%
Pfizer CentreOneUSD 373M+7%
The swing · year on year
Product revenues-USD 91M
Alliance revenues+USD 424M
Total revenue rose USD 381M: alliances added USD 424M and royalties USD 48M, while the medicines Pfizer sells itself fell USD 91M.
Revenue mix · year on year
Product revenuessold directlyUSD 11.86B-1%
Alliance revenuespartneredUSD 2.7B+19%
Royalty revenueslicensed outUSD 474M+11%
Total revenuesoperational +1%USD 15.03B+3%
Below the operating line
Other deductions netfrom USD 739MUSD 3.72B
Amortisation of intangiblesfrom USD 1.21BUSD 1.19B
Restructuring and acquisitionfrom a USD 18M creditUSD 457M
Tax benefitfrom a USD 141M charge-USD 407M
Reported tax ratefrom 4.6%62.4%
Deals & capital
  • Innovent Biologics development and commercialisation licence USD 650M up, USD 10.5B total
  • Arvinas development and commercialisation deal USD 70M up, USD 445M total
  • Chai Discovery contract service agreement
  • D&D Pharmatech contract service agreement
What held and what did not
  • SI&A expenses flat at USD 3.41B, down 1% operationally
  • R&D expenses up 13% to USD 2.81B, the fastest cost line
  • Cost of sales up to 27.2% of revenue from 25.8%
  • Pfizer CentreOne up 7% to USD 373M, the contract manufacturing arm
On the clock · next quarter
  • WatchProduct revenues whether the 1% decline is a base effect or a trend
  • WatchOther deductions USD 3.72B against USD 739M, unexplained in the extract
  • WatchH1 adjusted EPS USD 1.52 against USD 1.69, down 10%
H1 revenue USD 29.48B, +4%/H1 reported net income USD 2.44B, -58%/H1 adjusted income USD 8.73B, -10%, adjusted EPS USD 1.52 from USD 1.69/Cost of sales USD 4.09B, +8%/SI&A USD 3.41B, flat/Acquired IPR&D USD 16M from USD 2M
Synopulse
The Top Line · Q2 2026
Q2 2026 results release and condensed statements of operations · extracted 20 August 2026
What decides the next twelve months Whether product revenue turns. Alliance and royalty income carried the entire quarter, and that income is a share of what partners sell rather than something Pfizer controls. R&D is up 13 percent while the products it funds are down 1 percent, which is the right direction for the pipeline and the wrong one for this year. The $10.5 billion Innovent licence signals where Pfizer thinks the answer is, and none of it arrives inside twelve months.
13 Operating profit +48%

Operating profit rose 48 percent and gross profit rose 2.5 percent

Danaher’s operating profit rose 48.3 percent to $1,127 million on sales up 5.5 percent. Gross profit rose 2.5 percent. The gap between those two numbers is selling, general and administrative expense, which fell 12.2 percent, or $288 million, and did almost all the work.

Underneath, the margin went the wrong way. Cost of sales rose $241 million on sales up $329 million, so gross margin fell 171 basis points to 57.6 percent from 59.4 percent. Research and development rose only 2.2 percent to $412 million, taking R&D to 6.6 percent of sales from 6.8 percent.

Growth is less organic than the headline. Total sales growth of 5.5 percent breaks into 3.0 percent core, 1.5 points from acquisitions and 1.0 point from currency. Respiratory testing added a further 1.5 points, so core growth excluding respiratory was 4.5 percent. Diagnostics grew 7.0 percent in total and 2.0 percent core, with acquisitions worth 4 points.

Reported and adjusted earnings tell different stories. Diluted EPS rose 59.7 percent to $1.23 against a prior quarter depressed by impairments worth $0.60 a share. Adjusted diluted EPS rose 7.8 percent to $1.94, with acquisition amortisation of $0.65 a share the largest reconciling item.

13Mkt cap Danaher NYSE DHR · Mkt cap USD 148.68B
Total revenue
USD 6.26B
+5.5%reported+3.0%core
Revenue added
+USD 329M
From USD 5.94B, core growth 3.0%
Profit margin
18.0%+520bp
Operating margin, from 12.8%
R&D expense
USD 412M+2.2%
6.6% of sales, from 6.8%
Adjusted EPS
USD 1.94+7.8%
Reported USD 1.23, from USD 0.77
Gross margin
57.6%-171bp
Gross profit USD 3.61B
The swing · year on year
Cost of sales added-USD 241M
Sales added+USD 329M
Cost rose almost as fast as sales, so gross profit gained only USD 88M. Operating profit still rose USD 367M because SG&A fell USD 288M.
Sales growth by segment · Q2
Diagnosticscore 2.0%+7.0%
Life Sciencescore 5.5%+5.5%
Biotechnologycore 2.5%+4.0%
Total companycore 3.0%+5.5%
Core ex-respiratorycompany+4.5%
What moved the profit
Salesfrom USD 5.94BUSD 6.26B+5.5%
Gross profitfrom USD 3.52BUSD 3.61B+2.5%
SG&Afrom USD 2.36BUSD 2.07B-12.2%
Operating profitfrom USD 760MUSD 1.13B+48.3%
Net earningsfrom USD 555MUSD 870M+56.8%
Growth bridge · total to core
  • Total sales growth 5.5% reported
  • Acquisitions 1.5 points of the 5.5
  • Currency 1.0 point of the 5.5
  • Core sales growth 3.0%, or 4.5% excluding respiratory testing
Below the operating line
  • Interest expense USD 107M against USD 71M
  • Interest income USD 61M against USD 8M
  • Effective tax rate 19.3% against 15.3%
  • Diluted shares 707.6M against 719.1M, down 1.6%
On the clock · next quarter
  • WatchGross margin down 171 basis points, the SG&A cut cannot repeat indefinitely
  • WatchRespiratory testing worth 1.5 points of company growth and 3.0 points of Biotechnology
  • WatchDiagnostics 7.0% total against 2.0% core, four points from acquisitions
Cost of sales USD 2.65B, from USD 2.41B/Other expense USD 3M, from USD 42M/Earnings before taxes USD 1.08B, +64.6%/Income taxes USD 208M, effective rate 19.3% from 15.3%/Acquisition amortisation USD 463M pretax, USD 0.65 a share/Acquisition-related charges USD 0.15 a share, nil a year ago
Synopulse
The Top Line · Q2 2026
Q2 2026 consolidated condensed statements of earnings and non-GAAP reconciliation · extracted 20 August 2026
What decides the next twelve months Whether the cost cut was structural or timing. A 12.2 percent fall in SG&A produced a 48 percent rise in operating profit while gross margin fell 171 basis points, and only one of those two things can carry a company for long. Core growth of 3.0 percent, or 4.5 percent excluding respiratory testing, is the honest run rate, and Diagnostics at 2.0 percent core against 7.0 percent reported shows how much of the top line is bought rather than grown.
14 H1 +20.7% · tax doubled

Pre-tax income rose $114 million and net income fell

Intuitive earned $1,054.6 million before tax in the quarter against $940.4 million in the first quarter, an increase of $114.2 million. Net income was $823.2 million against $826.0 million, a fall of $2.8 million. The entire difference is tax: the charge went from $114.4 million to $231.4 million, and the effective rate from 12.2 percent to 21.9 percent.

The trading business is compounding hard. Revenue rose 4.4 percent sequentially to $2,892.3 million and 20.7 percent year on year across the half to $5,663.1 million. All three lines grew together in the half: instruments and accessories up 20.4 percent, systems up 21.7 percent and services up 20.1 percent, which is the balance you want in a placed-base business.

Margins improved as volume scaled. Gross margin reached 67.8 percent against 66.1 percent in the first quarter, and 66.9 percent in the half against 65.5 percent, up 141 basis points. Cost of revenue actually fell in absolute terms quarter on quarter, to $931.9 million from $940.3 million, while revenue rose $121.5 million.

Investment is rising with it. Research and development was $370.6 million, 12.8 percent of revenue, and $732.5 million in the half, up 16.4 percent. Selling and administrative costs rose only 9.5 percent in the half against revenue up 20.7 percent, which is why half-year operating income rose 38.3 percent to $1,827.2 million.

14Mkt cap Intuitive Surgical NASDAQ ISRG · Mkt cap USD 142.49B
Total revenue
USD 2.89B
+4.4%vs Q1+20.7%H1 YoY
Revenue added
+USD 122M
On Q1 2026, +20.7% across the half
Profit margin
33.6%+270bp
Operating margin, on Q1 2026
R&D expense
USD 370.6M+2.4%
12.8% of revenue, +16.4% in H1
Diluted EPS
USD 2.29+0.4%
H1 USD 4.57, from USD 3.72, +22.9%
Gross margin
67.8%+172bp
Gross profit USD 1.96B
Revenue line · half year, year on year
Instruments, accessoriesH1 2026USD 3.42B+20.4%
SystemsH1 2026USD 1.34B+21.7%
ServicesH1 2026USD 906M+20.1%
The swing · on the first quarter
Income tax added-USD 117.0M
Pre-tax income added+USD 114.2M
The tax charge grew USD 117.0M against pre-tax income up USD 114.2M, so net income fell USD 2.8M. The effective rate went from 12.2% to 21.9%.
Quarter on quarter · Q2 against Q1 2026
Instruments and accessoriesfrom USD 1.69BUSD 1.74B+2.9%
Systemsfrom USD 650.7MUSD 685M+5.3%
Servicesfrom USD 433.7MUSD 472M+8.9%
Total revenuefrom USD 2.77BUSD 2.89B+4.4%
Income from operationsfrom USD 855.3MUSD 972M+13.6%
Half year · year on year
Total revenuefrom USD 4.69BUSD 5.66B+20.7%
Gross profitfrom USD 3.08BUSD 3.79B+23.3%
Operating expensesfrom USD 1.75BUSD 1.96B+12.0%
Income from operationsfrom USD 1.32BUSD 1.83B+38.3%
Net income to Intuitivefrom USD 1.36BUSD 1.64B+20.8%
What scaled
  • Gross margin 67.8% in the quarter, up 172 basis points on Q1
  • Cost of revenue fell to USD 931.9M from USD 940.3M while revenue rose USD 121.5M
  • Operating margin 33.6% against 30.9% in the first quarter
  • Services the fastest sequential line at 8.9%
Below the operating line
  • Interest and other income USD 82.7M against USD 85.1M
  • Effective tax rate 21.9% against 12.2%, and 17.3% in the half against 8.8%
  • Excess tax benefits USD 17.3M against USD 73.3M in the first quarter
  • Diluted shares 357.3M against 359.8M
On the clock · next quarter
  • WatchTax rate whether 21.9% is the new run rate after two quarters of low single digits
  • WatchSystems USD 685M placed in the quarter, the leading indicator for instrument revenue
  • WatchR&D up 16.4% in the half, ahead of SG&A at 9.5%
Cost of revenue USD 931.9M, product USD 777.0M and service USD 154.9M/SG&A USD 617.9M, from USD 613.3M/Income before taxes USD 1.05B, from USD 940.4M/Net income attributable to Intuitive USD 818.1M, from USD 821.5M/Noncontrolling interests USD 5.1M/Intangible amortisation USD 24.0M, from USD 7.1M
Synopulse
The Top Line · Q2 2026
Q2 2026 unaudited quarterly and year-to-date statements of income · extracted 20 August 2026
What decides the next twelve months Tax, not trading. Revenue grew 20.7 percent in the half with all three revenue lines moving together and gross margin up 141 basis points, which is as clean a growth picture as anything in this edition. The only thing that went backwards was net income, and it went backwards because the effective rate nearly doubled to 21.9 percent. If that rate holds, reported earnings growth lags revenue growth by roughly ten points regardless of how many systems get placed.
15 Revenue +5.7% · EPS tripled

Earnings tripled because a charge did not repeat, not because the business tripled

Bristol Myers Squibb reported diluted earnings per share of USD 1.62 against USD 0.64, and net earnings of USD 3,317M against USD 1,310M. Revenue grew 5.7 percent. The gap between those two rates is one line that was there last year and is not there now: acquired IPR&D of USD 1,508M in the second quarter of 2025, the BioNTech upfront, against nil this quarter.

Underneath, the portfolio is turning over fast. The Growth Portfolio grew 14.6 percent to USD 7,560M, led by Camzyos up 60 percent, Breyanzi up 40.7 percent and Reblozyl up 29.4 percent. Cobenfy nearly doubled to USD 63M and Opdivo Qvantig, the subcutaneous version, reached USD 261M from USD 30M while base Opdivo fell 2.9 percent.

The Legacy Portfolio fell 4.4 percent to USD 5,422M, and inside it the erosion is severe. Pomalyst fell 71.2 percent to USD 204M and Revlimid 49.3 percent to USD 425M, shedding USD 917M between them. What held the line was Eliquis, up 21.8 percent to USD 4,481M and now the single largest product in the company, adding USD 801M on its own.

Costs moved the right way. Amortisation of acquired intangibles halved to USD 437M, restructuring reversed to a USD 32M credit, and the effective tax rate fell to 18.8 percent from 25.9 percent. Against that, research and development rose 14.7 percent to USD 2,959M, which is 22.8 percent of revenue, including USD 220M for a priority review voucher.

15Mkt cap Bristol Myers Squibb NYSE BMY · Mkt cap USD 138.11B
Total revenue
USD 12.97B
+5.7%reported+5.7%product sales
Revenue added
+USD 704M
From USD 12.27B, +5.7%
Profit margin
31.5%+1,705bp
Pre-tax margin, from 14.5%
R&D expense
USD 2.96B+14.7%
22.8% of revenue, from 21.0%
Diluted EPS
USD 1.62+153%
From USD 0.64, GAAP
Gross margin
71.3%-124bp
Excludes intangible amortisation
Sales by region · as reported
USD 12.97B Q2 REVENUE
United StatesUSD 8.99B · +5.5%69.3%
InternationalUSD 3.66B · +5.3%28.2%
OtherUSD 318M · +17.8%2.5%
Portfolio and product · year on year
Growth Portfolio USD 7.56B +14.6%Legacy Portfolio USD 5.42B -4.4%
EliquisLegacyUSD 4.48B+21.8%
OpdivoGrowthUSD 2.48B-2.9%
OrenciaGrowthUSD 1.03B+7.4%
YervoyGrowthUSD 769M+5.6%
ReblozylGrowthUSD 735M+29.4%
BreyanziGrowthUSD 484M+40.7%
RevlimidLegacyUSD 425M-49.3%
CamzyosGrowthUSD 416M+60.0%
PomalystLegacyUSD 204M-71.2%
The swing · year on year
Revlimid and Pomalyst-USD 917M
Eliquis+USD 801M
The two eroding myeloma brands shed USD 917M and Eliquis alone added USD 801M. The Growth Portfolio added a further USD 964M.
Growth Portfolio · top 5
Opdivobase formulationUSD 2.48B-2.9%
OrenciaimmunologyUSD 1.03B+7.4%
YervoyoncologyUSD 769M+5.6%
ReblozylhaematologyUSD 735M+29.4%
Breyanzicell therapyUSD 484M+40.7%
Legacy Portfolio · the run-off
Eliquislargest productUSD 4.48B+21.8%
Revlimidfrom USD 838MUSD 425M-49.3%
Pomalyst / Imnovidfrom USD 708MUSD 204M-71.2%
Sprycelfrom USD 120MUSD 88M-26.7%
Legacy totalfrom USD 5.67BUSD 5.42B-4.4%
Milestones this quarter
  • ASCO data across the oncology franchise
  • CELMoDs iberdomide and mezigdomide advancing toward commercialisation
  • Iza-bren fourth global pivotal trial starting in 1L EGFR-mutant NSCLC
  • Pumitamig Phase 2 combination study starting with imzokitug
What changed the earnings
  • Acquired IPR&D nil this quarter against USD 1,508M last, the BioNTech upfront
  • Intangible amortisation USD 437M against USD 830M, roughly halved
  • Restructuring a USD 32M credit against a USD 279M charge
  • Effective tax rate 18.8 percent against 25.9 percent
On the clock · next quarter
  • PDUFAIberdomide FDA decision 17 August 2026 in relapsed refractory myeloma
  • PaymentHengrui USD 600M upfront due in Q3 for thirteen early-stage assets
  • PaymentBioNTech anniversary payments begin in Q3, USD 2.0B in aggregate to 2028
  • WatchPomalyst down 71.2 percent, the steepest product decline in this edition
Net product sales USD 12.59B, alliance and other revenue USD 385M/Cost of products sold USD 3.73B, excludes amortisation/SG&A USD 1.83B, 14.1% of revenue/Amortisation of acquired intangibles USD 437M from USD 830M/Earnings before taxes USD 4.09B from USD 1.77B/Diluted shares 2,048M
Synopulse
The Top Line · Q2 2026
Q2 2026 Form 10-Q, consolidated statements of earnings · extracted 20 August 2026
What decides the next twelve months The run-off against the ramp. Revlimid and Pomalyst shed USD 917 million in a single quarter and Eliquis, now the largest product at USD 4,481 million, is itself a legacy brand facing US price negotiation. The Growth Portfolio at USD 7,560 million is growing 14.6 percent and has to get much larger before the legacy decline stops mattering. This quarter’s tripled earnings are an easy comparison, not a step change.
16 Beat · gross margin +450bp

Sales rose 9.4 percent and the cost of making them fell

Stryker sold $6,589 million, up 9.4 percent, and its cost of sales fell 4.1 percent to $2,091 million. Revenue up $567 million against cost down $90 million produced $657 million of extra gross profit, and gross margin jumped 450 basis points to 68.3 percent from 63.8 percent.

Operating expenses rose only $111 million against that. Research and engineering grew 6.6 percent to $434 million and selling and administrative costs 7.2 percent to $2,229 million, both slower than sales. Operating income therefore rose 49.1 percent to $1,659 million and the operating margin went from 18.5 percent to 25.2 percent.

The prior-year comparator flatters the picture slightly. Last year’s quarter carried $55 million of goodwill and other impairments against $1 million this year, and intangible amortisation fell from $187 million to $175 million. Neither explains a 450 basis point gross margin move, which is manufacturing and mix.

Below the line, tax took more. The effective rate rose to 18.4 percent from 13.0 percent, so net earnings grew 44.3 percent while pre-tax earnings grew 53.9 percent. Diluted earnings per share reached $3.30 against $2.29. Across the half, sales grew 6.1 percent and operating income 33.1 percent.

16Mkt cap Stryker NYSE SYK · Mkt cap USD 130.4B
Total revenue
USD 6.59B
+9.4%reported+17.1%gross profit
Revenue added
+USD 567M
From USD 6.02B, cost of sales fell USD 90M
Profit margin
25.2%+670bp
Operating margin, from 18.5%
R&D expense
USD 434M+6.6%
6.6% of sales, research and engineering
Diluted EPS
USD 3.30+44.1%
H1 USD 5.23, from USD 3.98
Gross margin
68.3%+450bp
Gross profit USD 4.5B
Income statement · year on year
Net salesfrom $6,022MUSD 6.59B+9.4%
Gross profitfrom $3,841MUSD 4.5B+17.1%
Operating expensesfrom $2,728MUSD 2.84B+4.1%
Cost of salesfrom $2,181MUSD 2.09B-4.1%
Operating incomefrom $1,113MUSD 1.66B+49.1%
Net earningsfrom $884MUSD 1.28B+44.3%
The swing · year on year
Operating expenses added-USD 111M
Gross profit added+USD 657M
Cost of sales fell USD 90M while sales rose USD 567M, so gross profit gained USD 657M against only USD 111M of extra operating cost.
Margin · % of sales
Gross marginfrom 63.8%68.3%
Operating marginfrom 18.5%25.2%
R&D and engineeringfrom 6.8%6.6%
Selling and administrativefrom 34.5%33.8%
Effective tax ratefrom 13.0%18.4%
Half year · year on year
Net salesfrom USD 11.89BUSD 12.61B+6.1%
Gross profitfrom USD 7.58BUSD 8.31B+9.5%
Operating incomefrom USD 1.95BUSD 2.6B+33.1%
Net earningsfrom USD 1.54BUSD 2.02B+31.4%
Total assetsfrom USD 47.84B at DecemberUSD 47.93B+0.2%
What moved the margin
  • Cost of sales fell 4.1 percent in absolute terms while sales rose 9.4 percent
  • Impairments USD 1M this quarter against USD 55M a year ago
  • Intangible amortisation USD 175M against USD 187M, down 6.4 percent
  • Operating expenses up 4.1 percent, less than half the rate of sales
Balance sheet
  • Cash and equivalents USD 3.39B against USD 4.01B at December
  • Inventories USD 5.52B against USD 5.31B
  • Long-term debt USD 14.19B against USD 14.86B
  • Shareholders’ equity USD 23.99B against USD 22.42B
On the clock · next quarter
  • WatchGross margin whether 68.3 percent holds without the weak prior-year comparator
  • WatchTax rate 18.4 percent against 13.0 percent, five points of earnings drag
  • WatchInventories up USD 211M since December against a falling cost of sales
Cost of sales USD 2.09B, down 4.1%, 31.7% of sales from 36.2%/Selling and administrative USD 2.23B, +7.2%/Amortisation of intangibles USD 175M from USD 187M/Goodwill and other impairments USD 1M from USD 55M/Other expense net USD 95M from USD 97M/Earnings before income taxes USD 1.56B, +53.9%
Synopulse
The Top Line · Q2 2026
Q2 2026 consolidated statements of earnings and balance sheet · extracted 20 August 2026
What decides the next twelve months Whether 68.3 percent is the new gross margin. A 450 basis point move in one quarter, achieved with cost of sales falling in absolute terms, is the largest margin gain in this edition and it did most of the work behind a 49 percent rise in operating income. Part of the comparison is easy, since last year carried $55 million of impairments. The tax rate going from 13.0 to 18.4 percent is the offset that will persist.
17 Revenue +13.7% · on a 14-week quarter

An extra week of selling sits inside a 13.7 percent growth rate

Medtronic’s revenue grew 13.7 percent to USD 9,756M, and the first thing to know about that number is that fiscal 2027 is a 53-week year with the extra week falling in this quarter. Against a 13-week comparative, roughly one fourteenth of the period had no counterpart a year ago. The reported rate flatters the underlying one by something close to seven points.

Even allowing for that, Cardiovascular is running hard. The segment grew 19.5 percent to USD 3,927M, and inside it Electrophysiology Therapies grew 29.6 percent to USD 2,218M, adding USD 506M. That single division is 22.7 percent of company revenue and produced 43 percent of the company’s growth.

The rest is steadier. Neuroscience grew 10.3 percent to USD 2,678M and Medical Surgical 9.9 percent to USD 2,279M, the segment that was flat in the United States a year ago. Diabetes, no longer a reportable segment since the MiniMed IPO in March, grew 16.9 percent to USD 843M and is still consolidated because Medtronic retains control.

Margins moved only slightly. Gross margin was 65.0 percent, unchanged, while operating profit rose 22.1 percent to USD 1,764M and the operating margin gained 124 basis points to 18.1 percent. Diluted earnings per share reached USD 1.14 against USD 0.81, helped by an effective tax rate of 16.3 percent against 19.6 percent.

17Mkt cap Medtronic NYSE MDT · Mkt cap USD 120.48B
Total revenue
USD 9.76B
+13.7%reported+14.1%segments
Revenue added
+USD 1.18B
From USD 8.58B, on a 14-week quarter
Profit margin
18.1%+124bp
Operating margin, from 16.8%
R&D expense
USD 771M+6.2%
7.9% of sales, from 8.5%
Diluted EPS
USD 1.14+40.7%
From USD 0.81, GAAP
Gross margin
65.0%-3bp
Excludes intangible amortisation
Sales by region · as reported
USD 9.76B Q1 FY27 SALES
United StatesUSD 4.91B · +16.1%50.3%
InternationalUSD 4.85B · +11.4%49.7%
Segment and division · year on year
Cardiovascular USD 3.93B +19.5%Neuroscience USD 2.68B +10.3%Medical Surgical USD 2.28B +9.9%
Electrophysiology Ther.CardiovascularUSD 2.22B+29.6%
Surgical, EndoscopyMedical SurgicalUSD 1.74B+8.7%
Cranial, Spinal Tech.NeuroscienceUSD 1.36B+12.7%
Interventional Cardio.CardiovascularUSD 894M+7.2%
Diabetesno longer a segmentUSD 843M+16.9%
Specialty TherapiesNeuroscienceUSD 774M+10.3%
NeuromodulationNeuroscienceUSD 539M+4.9%
Acute Care, MonitoringMedical SurgicalUSD 539M+14.4%
CardioVascular SurgeryCardiovascularUSD 477M+9.4%
The swing · fastest against slowest
Neuromodulation added+USD 25M
Electrophysiology added+USD 506M
Electrophysiology Therapies is 22.7% of revenue and produced 43% of the company’s growth. Neuromodulation, the slowest line, grew 4.9%.
Cardiovascular · the engine
Electrophysiology Therapiesfrom USD 1,712MUSD 2.22B+29.6%
Interventional Cardiologyfrom USD 834MUSD 894M+7.2%
CardioVascular Surgeryfrom USD 436MUSD 477M+9.4%
Peripheral Vascular Healthfrom USD 302MUSD 338M+11.9%
Segment totalfrom USD 3,285MUSD 3.93B+19.5%
Income statement · year on year
Cost of products sold35.0% of salesUSD 3.42B+13.8%
SG&A32.8% of salesUSD 3.2B+14.0%
R&D7.9% of salesUSD 771M+6.2%
Operating profit18.1% marginUSD 1.76B+22.1%
Net income to Medtronicfrom USD 1,040MUSD 1.47B+41.3%
Read the period carefully
  • 53-week year fiscal 2027 carries an extra week, and it falls in this quarter
  • Comparative the prior quarter ended 25 July 2025 and ran 13 weeks
  • Fiscal calendar Medtronic’s year ends in late April, so this is fiscal Q1
  • Segment recast Cardiovascular divisions renamed and prior periods restated this quarter
Deals & capital
  • CathWorks remaining shares acquired 20 April 2026 USD 718M
  • Scientia Vascular acquired 12 June 2026, neurovascular access USD 681M
  • SPR Therapeutics acquired 16 July 2026, peripheral nerve stimulation USD 654M
  • Returned to holders USD 921M of dividends and USD 267M of buyback
On the clock · next quarter
  • WatchUnderlying growth the first clean 13-week comparison since the extra week
  • WatchMiniMed still consolidated after the March IPO, separation restructuring runs to FY29
  • WatchNeuromodulation 4.9 percent, the slowest division in the company
Fiscal 2027 is a 53-week year and the extra week falls in this quarter/Reportable segment sales USD 8.88B, +14.1%/Amortisation of intangibles USD 412M from USD 459M/Restructuring charges USD 72M from USD 45M/Income before taxes USD 1.77B, +35.9%/Effective tax rate 16.3% from 19.6%, diluted shares 1,285.1M
Synopulse
The Top Line · Q2 2026
Fiscal Q1 2027 Form 10-Q, quarter ended 31 July 2026 · extracted 20 August 2026
What decides the next twelve months Whether the growth survives a normal quarter. A 53-week year puts an extra week of selling into this comparison, so 13.7 percent is not the run rate and the next quarter is the first clean read. What looks durable underneath is Electrophysiology Therapies at USD 2,218 million and growing 29.6 percent, now nearly a quarter of the company. What does not is Neuromodulation at 4.9 percent, and a Medical Surgical segment that has spent a year at single digits.
18 Sales +17.8% at CER

Dupixent is 44 percent of the company and four fifths of its growth

Dupixent sold EUR 5,154M in the quarter, up 37.6 percent at constant rates, and is now 44.4 percent of everything Sanofi sells. Of the EUR 1,603M the company added year on year, Dupixent contributed roughly EUR 1,322M, which is 82 percent of the growth. Everything else in the portfolio added about EUR 281M between it.

In the United States the concentration is sharper still. Dupixent took €3,899 million there, growing 42.8 percent, against €6,344 million of total US sales. Three quarters of what Sanofi sells in its largest market is one molecule.

The launch cohort behind it is real but small. Pharma launches reached €1,305 million, up 48.3 percent, and including vaccines the launch portfolio was €1,530 million, up 61.1 percent. Ayvakit at €190 million and Wayrilz at €17 million are new to the table, and Sarclisa grew 35.7 percent to €187 million.

The erosion is spread thinly rather than concentrated. Influenza and COVID-19 vaccines fell 61.7 percent to €54 million, industrial sales fell 25.5 percent, Myozyme fell 22.9 percent and Lovenox 15.8 percent. Lantus, still €394 million, fell 7.0 percent and 17.1 percent in the United States.

18Mkt cap Sanofi NASDAQ SNY · EPA SAN · Mkt cap USD 109.81B
Total revenue
EUR 11.6B
+16.0%reported+17.8%CER
Revenue added
+EUR 1.6B
From EUR 9.99B, +16.0%
Profit margin
28.2%+360bp
Business operating margin
R&D expense
EUR 2.23B+17.0%
19.3% of net sales, from 19.1%
Business EPS
EUR 2.09+31.4%
Business net income EUR 2.5B
Gross margin
80.6%+360bp
Business gross profit EUR 9.35B
Franchise · CER growth, year on year
DupixentImmunologyEUR 5.15B+37.6%
Other main medicinesestablishedEUR 2.87B-2.9%
Rare diseasesfranchiseEUR 1.89B+13.0%
VaccinesfranchiseEUR 1.15B-3.5%
OncologySarclisa, JevtanaEUR 257M+28.0%
KevzaraImmunologyEUR 177M+35.1%
Industrial salescontractEUR 109M-25.5%
The swing · year on year
Influenza, COVID-19 vaccines-EUR 87M
Dupixent+EUR 1.32B
Dupixent added about EUR 1.32B of the company’s EUR 1.6B increase. The rest of the portfolio, more than thirty products, added roughly EUR 281M between it.
Top 5 · by revenue, CER growth
DupixentImmunologyEUR 5.15B+37.6%
LantusDiabetesEUR 394M-7.0%
ToujeoDiabetesEUR 354M+4.4%
ALTUVIIIORare diseaseEUR 349M+23.7%
Meningitis, travel vaccinesVaccinesEUR 287M-5.9%
Launching and eroding
Ayvakitnew to the tableEUR 190Mnew
SarclisaOncologyEUR 187M+35.7%
BeyfortusVaccinesEUR 108M+54.2%
Influenza, COVID-19VaccinesEUR 54M-61.7%
Industrial salescontract manufacturingEUR 109M-25.5%
The launch cohort
  • Pharma launches €1,305M, up 48.3 percent at constant rates
  • All launches €1,530M including vaccines, up 61.1 percent
  • Ayvakit €190M, new to the disclosure table
  • Wayrilz €17M, entirely in the United States
Fastest growing lines
  • Qfitlia €7M from a standing start, all United States
  • Beyfortus up 54.2 percent to €108M
  • Dupixent up 37.6 percent, and 42.8 percent in the United States
  • Sarclisa up 35.7 percent to €187M
On the clock · next quarter
  • WatchDupixent concentration 44.4 percent of sales and 80 percent of growth
  • WatchVaccines influenza and COVID-19 down 61.7 percent, the fastest decline on the card
  • WatchEstablished portfolio Lantus, Lovenox, Plavix and Multaq all falling
Business gross profit EUR 9.35B, 80.6% of net sales from 77.0%/Cost of sales EUR 2.83B, 24.4% of net sales from 29.3%/Selling and general EUR 2.42B, 20.9% from 22.5%/Business operating income EUR 3.28B, +33.5%/Business net income EUR 2.5B, +28.9%, tax rate 21.7%/H1 net sales EUR 22.11B, business EPS EUR 3.97
Synopulse
The Top Line · Q2 2026
Q2 2026 business net income statement · extracted 20 August 2026
What decides the next twelve months How long one molecule can carry a company. Dupixent at 44.4 percent of sales and 80 percent of growth is the highest single-asset concentration in this edition, higher than Keytruda at Merck or HIV at Gilead. The launch cohort at €1,530 million is growing 61 percent and is the intended answer, but it is currently one eighth of the size of the product it is meant to succeed.
19 Core +6% · total profit -76%

Core operating profit rose 6 percent and total operating profit fell 76 percent

On GSK’s core measure the quarter was strong: sales up 5 percent to £8,409 million, gross margin up 230 basis points to 77.4 percent, operating profit up 6 percent to £2,800 million and core earnings per share up 9 percent to 50.5 pence.

On the statutory measure it was not. Total operating profit was £481 million against £2,023 million, down 76 percent, and the total operating margin fell from 25.3 percent to 5.7 percent, a drop of 1,960 basis points. Total earnings per share fell 69 percent to 10.8 pence. The gap between the two measures is £2,319 million, and GSK attributes it principally to the impairment of camlipixant.

The underlying cost picture is genuinely improving. Cost of sales fell 4 percent to £1,898 million while sales rose 5 percent, which is what produced the 230 basis point gross margin gain, helped by product mix and an easy prior-year comparator. Selling and administrative costs rose 5 percent, in line with sales.

Research spending is going the other way on purpose. R&D rose 13 percent to £1,721 million, or 20.5 percent of sales, which GSK describes as accelerated pipeline investment. Royalties fell 17 percent to £204 million against a prior year that included an intellectual property settlement, and core EPS benefited from buybacks and a lower tax rate.

19Mkt cap GSK NYSE GSK · LON GSK · Mkt cap USD 105.9B
Total revenue
GBP 8.41B
+5%reported+5%CER
Revenue added
+GBP 423M
From GBP 7.99B, +5% at CER
Profit margin
33.3%+40bp
Core operating margin, total 5.7%
R&D expense
GBP 1.72B+13%
20.5% of sales, from 19.1%
Core EPS
50.5p+9%
Total EPS 10.8p, from 35.5p
Gross margin
77.4%+230bp
Core gross profit GBP 6.51B
Core income statement · year on year
Salesfrom £7,986MGBP 8.41B+5%
Gross profitfrom £6,000MGBP 6.51B+9%
Core operating profitfrom £2,631MGBP 2.8B+6%
SG&Afrom £2,093MGBP 2.19B+5%
Cost of salesfrom £1,986MGBP 1.9B-4%
R&Dfrom £1,522MGBP 1.72B+13%
Total operating profitfrom £2,023MGBP 481M-76%
The swing · core against total
Total operating profit lost-GBP 1.54B
Core operating profit added+GBP 169M
Core operating profit rose £169M and total operating profit fell £1,542M. The £2,319M gap between the two measures is led by the camlipixant impairment.
Core against total
Operating profit, corefrom GBP 2.63BGBP 2.8B+6%
Operating profit, totalfrom GBP 2.02BGBP 481M-76%
Operating margin, corefrom 32.9%33.3%
Operating margin, totalfrom 25.3%5.7%
Earnings per share, totalfrom 35.5p10.8p
Margin bridge · Q2 2025 to Q2 2026
Q2 2025 core marginstarting point32.9%
Gross marginfavourable+2.5pp
SG&Aneutral0.0pp
R&Dadverse-1.4pp
Q2 2026 core margin at AERafter -0.2pp currency33.3%
What management attributed
  • Gross margin benefited from product mix and the prior-year comparator
  • SG&A up 5 percent, driven by the phasing of spend
  • R&D up 13 percent, accelerated pipeline investment
  • Royalties down 17 percent against a 2025 intellectual property settlement
Core EPS drivers
  • Buyback share count reduction supporting core EPS
  • Tax rate lower rate supporting core EPS
  • Core EPS 50.5 pence against 46.5 pence, up 9 percent at both AER and CER
  • Currency 0.2 points of drag on the core operating margin
On the clock · next quarter
  • Watchcamlipixant the impairment behind a 1,960 basis point fall in total operating margin
  • WatchR&D up 13 percent and costing 1.4 points of core margin
  • WatchRoyalties down 17 percent, no longer flattered by a settlement
Reported in pounds sterling · core results unless stated/Core cost of sales £1,898M, -4% at AER and -6% at CER/Core SG&A £2,194M, +5%/Royalties £204M from £246M, -17%/Core operating margin 33.3%, +40bps at AER and +60bps at CER/Total operating margin 5.7% from 25.3%
Synopulse
The Top Line · Q2 2026
Q2 2026 results presentation, core and total results · extracted 20 August 2026
What decides the next twelve months How much of the core measure survives contact with the statutory one. A single asset impairment took 1,960 basis points off the total operating margin, which is the largest single-item distortion in this edition, and it sits against a core business genuinely improving its gross margin by 230 basis points. The line to watch is R&D, up 13 percent and already costing 1.4 points of core margin, because that spend is the thing camlipixant was supposed to justify.
20 Beat · gross margin +306bp

Every region and every segment grew, and the smallest grew fastest

Boston Scientific grew 7.5 percent to $5,442 million, landing at the top of its own 5.5 to 7.5 percent guidance range. What is unusual is the spread: all four regions and both segments grew, and there is not a single declining line on the card.

Cardiovascular carried the volume, up 8.3 percent to $3,624 million, two thirds of the company. MedSurg grew 5.9 percent to $1,818 million, with Neuromodulation the fastest line anywhere in the business at 12.7 percent and Urology the slowest at 1.1 percent.

Geographically the smallest markets moved hardest. Latin America and Canada grew 21.9 percent to $206 million, and 16.2 percent operationally. Asia-Pacific grew 11.1 percent to $878 million. The United States, at $3,426 million and 63 percent of sales, grew 6.3 percent.

Margins did something unusual. Cost of products sold fell 2.6 percent to USD 1,594M while sales rose 7.5 percent, lifting gross margin 306 basis points to 70.7 percent. Operating expenses rose only 2.5 percent, so operating income climbed 43.8 percent to USD 1,178M and the operating margin gained 546 basis points to 21.7 percent. Reported diluted EPS was USD 0.61 against USD 0.53, and adjusted EPS USD 0.86.

20Mkt cap Boston Scientific NYSE BSX · Mkt cap USD 75.37B
Total revenue
USD 5.44B
+7.5%reported+8.0%operational
Revenue added
+USD 381M
From USD 5.06B, nothing declined
Profit margin
21.7%+546bp
Operating margin, from 16.2%
R&D expense
USD 554M+5.3%
10.2% of sales, from 10.4%
Adjusted EPS
USD 0.86
Reported GAAP USD 0.61 a share
Gross margin
70.7%+306bp
Gross profit USD 3.85B
Sales by region · as reported
USD 5.44B Q2 SALES
United StatesUSD 3.43B · +6.3%63.0%
EMEAUSD 932M · +6.2%17.1%
Asia-PacificUSD 878M · +11.1%16.1%
Latin America, CanadaUSD 206M · +21.9%3.8%
Segment and franchise · year on year
Cardiovascular USD 3.62B +8.3%MedSurg USD 1.82B +5.9%
CardiovascularsegmentUSD 3.62B+8.3%
MedSurgsegmentUSD 1.82B+5.9%
Endoscopyin MedSurgUSD 793M+7.6%
Urologyin MedSurgUSD 684M+1.1%
Neuromodulationin MedSurgUSD 341M+12.7%
The swing · fastest against slowest
Urology+USD 8M
Neuromodulation+USD 38M
Nothing declined this quarter. The spread runs from Urology at +1.1% to Neuromodulation at +12.7%, and Latin America and Canada at +21.9% is the fastest line on the card.
Segment · reported and organic
Cardiovascularorganic 7.8%USD 3.62B+8.3%
MedSurgorganic 5.4%USD 1.82B+5.9%
Endoscopyin MedSurgUSD 793M+7.6%
Urologyin MedSurgUSD 684M+1.1%
Neuromodulationin MedSurgUSD 341M+12.7%
Region · reported and operational
United Statesoperational 6.2%USD 3.43B+6.3%
EMEAoperational 4.2%USD 932M+6.2%
Asia-Pacificoperational 11.2%USD 878M+11.1%
Latin America, Canadaoperational 16.2%USD 206M+21.9%
Net salesguidance 5.5 to 7.5%USD 5.44B+7.5%
Cleared this quarter
  • TruSelect 2.6 Microcatheter FDA 510(k) clearance, embolization portfolio
  • FRACTURE trial met primary endpoints with the SEISMIQ 4CE system, presented at EuroPCR
  • AVANT GUARD FARAPULSE pulsed field ablation in persistent atrial fibrillation, Heart Rhythm 2026
  • ELEVATE-PF FARAFLEX mapping and ablation catheter feasibility study
Deals & capital
  • Penumbra agreed January 2026, thrombectomy, FTC second request pending, expected to close in H2 USD 14.5B
  • MiRus LLC 33.75% non-voting equity plus an option over the TAVR business for a further USD 3B USD 1.5B
  • Nalu Medical acquired 27 January 2026, chronic pain neuromodulation USD 523M
  • Share repurchase USD 2B completed, about 40 million shares
On the clock · next quarter
  • EnrollingFARADIGM pivotal trial of the FARAFLEX mapping and ablation catheter
  • WatchUrology 1.1% growth, the slowest line in the business
  • WatchLatin America, Canada 21.9% reported against 16.2% operational, a 5.7 point currency benefit
Cost of products sold USD 1.59B, down 2.6% on sales up 7.5%/SG&A USD 1.8B, +5.1%/Amortisation USD 233M, litigation charges USD 76M/Operating income USD 1.18B, +43.8%/Income before taxes USD 1.06B, effective rate 14.6% from 15.5%/Net income to common USD 907M, +13.8%, diluted shares 1,474.8M
Synopulse
The Top Line · Q2 2026
Q2 2026 Form 10-Q and results release · extracted 20 August 2026
What decides the next twelve months Whether the margin holds through Penumbra. Cost of products sold fell in absolute terms on 7.5 percent sales growth, which is the cleanest margin result in this edition, and nothing in the portfolio declined. Against that, Boston has committed USD 14.5 billion for Penumbra, still under FTC review, and USD 1.5 billion to MiRus with an option for USD 3 billion more. The balance sheet, not the trading, is where the next year gets decided.
21 Life Science up · Healthcare down

Life Science grew 8 percent organically and Healthcare shrank 3.4 percent

The two sectors in scope went in opposite directions. Life Science grew 8.0 percent organically to €2,412 million, adding about €181 million. Healthcare shrank 3.4 percent organically to €2,151 million, losing roughly €72 million on the same basis. Together they are €4,563 million, 84 percent of the Merck Group.

Healthcare’s reported number only clears zero because of dealmaking. Acquisitions contributed 5.4 percentage points and currency 0.3, so a 3.4 percent organic decline became roughly 2.3 percent reported growth. Nothing about the trading business improved; the perimeter changed.

Inside Life Science the strength is concentrated. Process Solutions, 44 percent of the sector, grew 14.7 percent organically to €1,071 million. Discovery Solutions grew only 2.1 percent to €724 million and Advanced Solutions 4.4 percent to €617 million. One business unit is carrying the sector.

At group level, including Electronics which sits outside this scope, net sales were €5,434 million, up 3.4 percent, with organic growth of 4.1 percent. Profitability fell across the board: operating result was €753 million against €891 million, down 15.5 percent, and the margin dropped from 17.0 percent to 13.9 percent.

21Mkt cap Merck KGaA ETR MRK · Mkt cap USD 69.51BHealthcare + Life Science
Total revenue
EUR 4.56B
+4.4%reported+2.9%organic
Revenue added
+EUR 193M
In-scope sectors, derived
Profit margin
13.9%-310bp
Group EBIT margin, from 17.0%
Sector and business unit · organic growth
Life Science EUR 2.41B +8.0% organicHealthcare EUR 2.15B -3.4% organic
Life Sciencein scopeEUR 2.41B+8.0%
Healthcarein scopeEUR 2.15B-3.4%
Process Solutionsin Life ScienceEUR 1.07B+14.7%
Electronicsout of scopeEUR 871M+11.7%
Discovery Solutionsin Life ScienceEUR 724M+2.1%
Advanced Solutionsin Life ScienceEUR 617M+4.4%
The swing · organic, year on year
Healthcare organic-EUR 72M
Life Science organic+EUR 181M
Healthcare fell 3.4% organically and only showed reported growth because acquisitions added 5.4 points. Life Science grew 8.0% organically with Process Solutions up 14.7%.
Growth bridge · organic, fx, acquisitions
Life Sciencefx -1.7, acq +0.1+8.0%
Healthcarefx +0.3, acq +5.4-3.4%
Electronicsfx -2.9, acq -10.6+11.7%
Merck Groupfx -1.1, acq +0.4+4.1%
Group net salesfrom EUR 5.25BEUR 5.43B+3.4%
Group profitability
Operating result, EBITfrom EUR 891MEUR 753M-15.5%
EBITDAfrom EUR 1.35BEUR 1.31B-2.4%
EBIT marginfrom 17.0%13.9%
H1 net salesfrom EUR 10.54BEUR 10.57B+0.3%
H1 EBIT marginfrom 18.0%16.0%
Scope note
  • In scope Healthcare €2,151M and Life Science €2,412M, 84 percent of the group
  • Out of scope Electronics €871M, 16 percent of the group
  • Combined in-scope sales €4,563M, derived by adding the two sectors
  • Profit measures reported at group level only, so EBIT and EBITDA above include Electronics
Life Science business units
  • Process Solutions €1,071M, 44 percent of the sector, organic growth 14.7 percent
  • Discovery Solutions €724M, 30 percent, organic growth 2.1 percent
  • Advanced Solutions €617M, 26 percent, organic growth 4.4 percent
  • Sector total €2,412M, organic growth 8.0 percent
On the clock · next quarter
  • WatchHealthcare organic minus 3.4 percent, masked by a 5.4 point acquisition contribution
  • WatchGroup EBIT margin 13.9 percent against 17.0 percent, down 310 basis points
  • WatchDiscovery Solutions 2.1 percent organic, the slowest Life Science unit
Reported in euros · scope is Healthcare and Life Science, Electronics excluded/Merck Group net sales €5,434M from €5,255M, +3.4%/Group operating result €753M from €891M, -15.5%, margin 13.9% from 17.0%/Group EBITDA €1,315M from €1,348M, -2.4%/H1 group net sales €10,568M from €10,535M/H1 operating result €1,690M from €1,897M, margin 16.0% from 18.0%
Synopulse
The Top Line · Q2 2026
Q2 2026 quarterly statement, net sales by business sector and business unit · extracted 20 August 2026
What decides the next twelve months Whether Healthcare stops shrinking without buying growth. Minus 3.4 percent organic, turned positive only by a 5.4 point acquisition contribution, is the weakest underlying line among the pharmaceutical names in this edition. Life Science is the offset and it is really Process Solutions at 14.7 percent, because the other two units grew 2.1 and 4.4 percent. Group EBIT margin down 310 basis points says neither sector is currently paying for the other.
22 Yen +10.2% · constant fx -0.5%

All of the growth was the yen, and net profit fell anyway

Takeda’s revenue rose 10.2 percent to ¥1,219.9 billion in yen and fell 0.5 percent at constant exchange rates. The underlying business shrank by about ¥5.5 billion and currency added roughly ¥118.7 billion. Every positive number on the top line is translation.

The pattern deepens down the statement. Operating profit rose 9.1 percent in yen and fell 3.1 percent at constant rates. Profit before tax rose 8.0 percent and fell 6.8 percent. By the time it reaches the bottom line even the yen cannot hold it up: net profit fell 8.9 percent to ¥113.3 billion, and 23.5 percent at constant rates.

Core measures are kinder but tell the same story. Core operating profit rose 11.5 percent in yen and fell 0.5 percent at constant rates, and core net profit rose 2.5 percent in yen against a 10.9 percent fall at constant rates. Core earnings per share were ¥154 against ¥151, up 1.5 percent reported and down 11.8 percent at constant rates.

This is the mirror image of Roche, five places above in this edition. Roche’s business grew 6 percent at constant rates and the Swiss franc turned it into a 2 percent decline. Takeda’s business shrank 0.5 percent at constant rates and the yen turned it into 10.2 percent growth. Neither number is wrong; they are answers to different questions.

22Mkt cap Takeda NYSE TAK · TSE 4502 · Mkt cap USD 58.56B
Total revenue
JPY 1,219.9B
+10.2%yen-0.5%CER
Revenue added
+JPY 113.2B
From JPY 1,106.7B, all of it currency
Profit margin
16.5%-20bp
Operating margin, core 29.4%
Core EPS
JPY 154+1.5%
Basic EPS JPY 71.65, from JPY 79.40
Reported and core · yen billions
RevenueCER -0.5%JPY 1,219.9B+10.2%
Core operating profitCER -0.5%JPY 358.9B+11.5%
Core net profitCER -10.9%JPY 242.9B+2.5%
Operating profitCER -3.1%JPY 201.4B+9.1%
Profit before taxCER -6.8%JPY 162.7B+8.0%
Net profitCER -23.5%JPY 113.3B-8.9%
The swing · year on year
Underlying at constant rates-JPY 5.5B
Currency+JPY 118.7B
The business shrank ¥5.5B at constant rates and the yen added ¥118.7B. Reported revenue rose ¥113.2B, all of it and more from translation.
Reported · in yen against at CER
RevenueCER -0.5%+10.2%
Operating profitCER -3.1%+9.1%
Profit before taxCER -6.8%+8.0%
Net profitCER -23.5%-8.9%
Basic EPSCER -24.2%-9.8%
Core · in yen against at CER
Core revenueCER -0.5%+10.2%
Core operating profitCER -0.5%+11.5%
Core net profitCER -10.9%+2.5%
Core EPSCER -11.8%+1.5%
Core EPS in yenfrom JPY 151JPY 154
Where reported and constant diverge
  • Revenue 10.7 points between +10.2 percent and -0.5 percent
  • Operating profit 12.2 points between +9.1 percent and -3.1 percent
  • Net profit 14.6 points between -8.9 percent and -23.5 percent
  • Basic EPS 14.4 points between -9.8 percent and -24.2 percent
The pairing
  • Roche at 05 grew 6 percent at CER and reported a 2 percent decline in francs
  • Takeda at 22 shrank 0.5 percent at CER and reported 10.2 percent growth in yen
  • Same quarter opposite currency effects on two companies of similar shape
  • Fiscal note Takeda’s year ends in March, so this is fiscal Q1 and the calendar period aligns
On the clock · next quarter
  • WatchConstant currency revenue minus 0.5 percent, the underlying line the yen is masking
  • WatchNet profit down 8.9 percent even in yen and 23.5 percent at constant rates
  • WatchCore to reported gap core operating profit ¥358.9B against reported ¥201.4B
Reported in Japanese yen, figures in billions · fiscal first quarter, calendar quarter to June/Revenue ¥1,219,900M from ¥1,106,685M, a ¥113,215M increase/Operating profit ¥201,417M from ¥184,566M/Profit before tax ¥162,718M from ¥150,630M/Net profit attributable to owners ¥113,197M from ¥124,243M/Basic EPS ¥71.65 from ¥79.40
Synopulse
The Top Line · Q2 2026
Q1 FY2027 financial results, reported and core · extracted 20 August 2026
What decides the next twelve months What happens when the yen stops helping. Revenue at constant rates is already negative and net profit is down 23.5 percent on the same basis, so the reported growth is a currency position rather than a commercial one. The gap between core operating profit at ¥358.9 billion and reported operating profit at ¥201.4 billion is the second thing to watch, because ¥157 billion of adjustments in a single quarter is a large amount of explaining.
23 Volume +5.1% · price -4.3%

They sold 5 percent more and were paid 4 percent less for it

Bayer’s pharmaceuticals division sold 5.1 percent more by volume and took 4.3 percent less on price. Add currency at minus 0.7 and portfolio at minus 0.4 and sales landed at €4,458 million, down 0.3 percent reported and up 0.8 percent adjusted. The quarter is a volume story cancelled by a price story.

Geographically it is not one business but two. Europe, the Middle East and Africa fell 17.8 percent to €1,393 million, shedding €301 million. North America grew 20.8 percent to €1,640 million, adding €282 million. Those two moves are 38.6 percentage points apart and almost exactly cancel: the division net lost €12 million.

The product mix behind it is a straight handover. Nubeqa and Kerendia continued to post significant gains, with Nubeqa growing in every region and strongest in the United States and Europe, while Radiology and the Mirena family also grew. Against that, Bayer recorded substantially lower Eylea and Xarelto sales on patent expirations.

Research spending fell while capital spending rose. R&D was €837 million against €959 million, down 12.7 percent, and capital expenditure was €290 million against €182 million, up 59.3 percent. Operating cash flow at the division collapsed to €80 million from €493 million, and at group level free cash flow was minus €371 million against plus €125 million.

23Mkt cap Bayer ETR BAYN · Mkt cap USD 55.59BPharmaceuticals only
Total revenue
EUR 4.46B
-0.3%reported+0.8%fx + portfolio
Revenue added
-EUR 12M-0.3%
From EUR 4.47B, volume +5.1% price -4.3%
Profit margin
23.7%-80bp
EBITDA margin before special items
R&D expense
EUR 837M-12.7%
18.8% of division sales, from EUR 959M
Core EPS
EUR 0.95-16.7%
Group, from EUR 1.14
EBITDA margin
23.7%-80bp
Before special items, from 24.5%
Sales by region · as reported
EUR 4.46B PHARMA Q2
North AmericaEUR 1.64B · +20.8%36.8%
Europe, Middle East, AfricaEUR 1.39B · -17.8%31.2%
Asia-PacificEUR 1.15B · -3.1%25.8%
Latin AmericaEUR 274M · +19.1%6.1%
Division by region · year on year
North Americaadj +23.6%EUR 1.64B+20.8%
Europe, ME, Africaadj -18.1%EUR 1.39B-17.8%
Asia-Pacificadj -0.6%EUR 1.15B-3.1%
Latin Americaadj +12.5%EUR 274M+19.1%
The swing · year on year
Europe, Middle East, Africa-EUR 301M
North America+EUR 282M
Two regions moved 38.6 percentage points apart and almost cancelled. Across all four the division net lost €12M.
Change in sales · components
VolumeH1 +4.7%+5.1%
PriceH1 -4.5%-4.3%
CurrencyH1 -3.2%-0.7%
PortfolioH1 -0.4%-0.4%
Reported salesfrom EUR 4.47BEUR 4.46B-0.3%
Division profitability
EBITDAfrom EUR 1.06BEUR 1.06B-0.3%
EBITDA before specialsfrom EUR 1.09BEUR 1.05B-3.6%
EBITfrom EUR 798MEUR 799M+0.1%
EBIT before specialsfrom EUR 830MEUR 795M-4.2%
Operating cash flowfrom EUR 493MEUR 80M-83.8%
Growing
  • Nubeqa significant gains in all regions, strongest in the United States and Europe
  • Kerendia continued significant gains
  • Radiology strong topline growth
  • Mirena family strong topline growth
Declining
  • Eylea substantially lower on patent expiration
  • Xarelto substantially lower on patent expiration
  • Price minus 4.3 percent across the division
  • R&D down 12.7 percent to €837M
On the clock · next quarter
  • WatchPrice minus 4.3 percent, cancelling a 5.1 percent volume gain
  • WatchEMEA down 17.8 percent, the steepest regional decline in this edition
  • WatchGroup free cash flow minus €371M in the quarter and minus €2,691M in the half
Group free cash flow -EUR 371M from +EUR 125M, division CapEx EUR 290M from EUR 182M/Reported in euros · scope is the Pharmaceuticals division, group figures marked as such/Division H1 sales €8,707M from €9,018M, -3.4% reported and +0.2% adjusted/Division special items +€4M from -€32M/Group sales €10,872M, +1.2% reported and +2.2% adjusted/Group EBITDA before specials €2,144M, margin 19.7% from 19.6%
Synopulse
The Top Line · Q2 2026
Q2 2026 Bayer Group key data and Pharmaceuticals division key data · extracted 20 August 2026
What decides the next twelve months Price. A division that grows volume 5.1 percent and still shrinks is being repriced faster than it can sell, and the named cause is Eylea and Xarelto coming off patent while Nubeqa and Kerendia are still filling in. The regional split makes it starker: North America up 20.8 percent against Europe down 17.8 percent means the recovery is one market deep. Group free cash flow at minus €2,691 million for the half is the constraint on how long that can be waited out.
24 Orders +14% · revenue +2%

Orders grew seven times faster than revenue

Orders rose 14 percent to €6,860 million and revenue rose 2 percent to €5,764 million. That is a book-to-bill of 1.19, and it means the company took in €1,096 million more work than it converted in the quarter. On a comparable basis orders grew 15 percent against revenue at 3 percent.

Profit rose 28 percent to €1,047 million and the margin went from 14.5 percent to 18.2 percent, a gain of 370 basis points. Excluding severance the margin was 18.6 percent against 15.1 percent. Management attributes the increase primarily to positive effects from tariff refunds in the United States, which is a one-off rather than an operating gain.

The revenue split inside the business is uneven. Volume growth came from imaging and precision therapy. Diagnostics declined, which Siemens attributes in part to a structural change in the market environment in China rather than a trading effect it expects to reverse quickly.

Currency worked against the quarter throughout, and profit still rose in every business. Severance costs fell to €24 million from €31 million. Note the calendar: Siemens Healthineers reports on a September year end, so its fiscal third quarter is the calendar quarter to June and aligns with this edition.

24Mkt cap Siemens Healthineers ETR SHL · Mkt cap USD 52.18B
Total revenue
EUR 5.76B
+2%reported+3%comparable
Revenue added
+EUR 102M
From EUR 5.66B, orders added EUR 836M
Profit margin
18.2%+370bp
Profit margin, 18.6% ex-severance
Orders and revenue · year on year
Orderscomparable +15%EUR 6.86B+14%
Revenuecomparable +3%EUR 5.76B+2%
Profitmargin 18.2%EUR 1.05B+28%
The swing · year on year
Revenue added+EUR 102M
Orders added+EUR 836M
Orders grew €836M against revenue up €102M, a book-to-bill of 1.19. Backlog is building faster than the company can convert it.
Quarter · actual and comparable
Ordersfrom EUR 6.02BEUR 6.86B+14%
Revenuefrom EUR 5.66BEUR 5.76B+2%
Profitfrom EUR 821MEUR 1.05B+28%
Severancefrom EUR 31MEUR 24M-23%
Book-to-billorders over revenue1.19
Margin
Profit marginfrom 14.5%18.2%
Excluding severancefrom 15.1%18.6%
Orders, comparableactual +14%+15%
Revenue, comparableactual +2%+3%
Currencymanagement notes adverse effectsheadwind
What grew
  • Imaging volume increase, and profit up most notably here
  • Precision therapy volume increase, and profit up most notably here
  • Orders 14 percent actual and 15 percent comparable
  • Profit up in all businesses despite adverse currency
What did not
  • Diagnostics revenue declined, in part on a structural change in the China market
  • Revenue 2 percent actual against orders at 14 percent
  • Currency adverse across the quarter
  • Margin quality the 370 basis point gain is primarily US tariff refunds
On the clock · next quarter
  • WatchTariff refunds the primary driver of a 370 basis point margin gain, and not repeatable
  • WatchBacklog conversion book-to-bill of 1.19 has to turn into revenue
  • WatchDiagnostics in China described as a structural market change
Reported in euros · fiscal third quarter, calendar quarter to June, aligned with this edition/Orders €6,860M from €6,024M, +14% actual and +15% comparable/Revenue €5,764M from €5,662M, +2% actual and +3% comparable/Profit €1,047M from €821M, +28%/Severance €24M from €31M/Profit margin 18.2% from 14.5%, and 18.6% from 15.1% excluding severance
Synopulse
The Top Line · Q2 2026
Q3 FY2026 results summary, Siemens Healthineers segment · extracted 20 August 2026
What decides the next twelve months Two things pulling opposite ways. A book-to-bill of 1.19 says demand is running well ahead of what the company is shipping, which is the strongest forward indicator on any card in this edition. Against that, the 370 basis point margin gain is attributed primarily to US tariff refunds rather than operations, and Diagnostics is shrinking on what Siemens itself calls a structural change in China. The backlog is real; this quarter’s margin is not the run rate.
25 Revenue +5.4% · guidance updated

The United States grew twice as fast as everywhere else

BD grew 5.4 percent to $4,983 million, or 4.4 percent on a currency-neutral basis. The split by geography is the striking part: the United States grew 6.9 percent reported and currency-neutral alike, while International grew 3.2 percent reported and only 0.6 percent once currency is stripped out.

All four segments grew. BioPharma Systems led at 6.6 percent reported and 5.2 percent currency-neutral, with Interventional close behind at 6.4 and 5.5 percent. Medical Essentials, the largest, grew 4.5 percent reported but 3.2 percent currency-neutral, the slowest underlying line in the business.

Cost structure is that of a device manufacturer rather than a pharmaceutical company. Cost of products sold was $2,668 million, 53.5 percent of revenue, leaving a gross margin of 46.5 percent. Research and development was $258 million, or 5.2 percent of revenue, roughly a quarter of what the pharmaceutical names in this edition spend proportionally.

Earnings moved almost exactly with sales. Reported diluted EPS rose 4.5 percent and 3.8 percent currency-neutral; adjusted diluted EPS rose 4.9 percent and 3.9 percent. BD updated its full-year guidance alongside the result. Note the calendar: BD’s financial year ends in September, so its fiscal third quarter is the calendar quarter to June and aligns with this edition.

25Mkt cap Becton Dickinson NYSE BDX · Mkt cap USD 51.09B
Total revenue
USD 4.98B
+5.4%reported+4.4%fx neutral
Revenue added
+USD 255M
From USD 4.73B, +5.4%
Profit margin
13.3%-234bp
Operating margin, from 15.6%
R&D expense
USD 258M
5.2% of revenue
Adjusted EPS
USD 3.23+4.9%
Reported USD 1.64, from USD 1.57
Gross margin
46.5%-83bp
Cost of products sold USD 2.67B
Segment · reported growth, year on year
BioPharma SystemsFX neutral +5.2%USD 66M+6.6%
InterventionalFX neutral +5.5%USD 64M+6.4%
Connected CareFX neutral +4.4%USD 49M+4.9%
Medical EssentialsFX neutral +3.2%USD 45M+4.5%
The swing · currency neutral
International+0.6%
United States+6.9%
Stripped of currency, the United States grew 6.9% and International 0.6%. International’s reported 3.2% is almost entirely translation.
Segment · reported and currency neutral
BioPharma SystemsFX neutral 5.2%+6.6%
InterventionalFX neutral 5.5%+6.4%
Connected CareFX neutral 4.4%+4.9%
Medical EssentialsFX neutral 3.2%+4.5%
Total revenuesFX neutral 4.4%+5.4%
Cost structure · % of revenue
Cost of products soldUSD 2.67B53.5%
Selling and administrativeUSD 1.26B25.3%
Research and developmentUSD 258M5.2%
Gross marginUSD 2.31B46.5%
Revenuesfrom about USD 4.73BUSD 4.98B+5.4%
Business highlights
  • Medical Essentials awarded a Vizient contract
  • BioPharma Systems announced a collaboration
  • Interventional launched the Elyra platform
  • Recognition named to TIME’s list, and issued the fiscal year sustainability report
Geography · reported and currency neutral
  • United States 6.9 percent reported and 6.9 percent currency neutral
  • International 3.2 percent reported and 0.6 percent currency neutral
  • Total 5.4 percent reported and 4.4 percent currency neutral
  • Guidance full-year outlook updated with the result
On the clock · next quarter
  • WatchInternational 0.6 percent currency-neutral growth, the weakest line on the card
  • WatchMedical Essentials largest segment, slowest underlying growth at 3.2 percent
  • NoteFebruary 2026 a basis of presentation change is noted in the source and is not detailed here
Fiscal third quarter, calendar quarter to June, aligned with this edition/Cost of products sold USD 2.67B, 53.5% of revenue/Selling and administrative USD 1.26B, 25.3%/Reported diluted EPS growth +4.5%, currency neutral +3.8%/Adjusted diluted EPS growth +4.9%, currency neutral +3.9%/Connected Care, BioPharma Systems and Interventional were reorganised effective October, per the source note
Synopulse
The Top Line · Q2 2026
Fiscal Q3 2026 results release and condensed consolidated statements · extracted 20 August 2026
What decides the next twelve months International. Currency-neutral growth of 0.6 percent outside the United States, against 6.9 percent inside it, means BD is currently a domestic growth story wearing a global cost base. Medical Essentials, the biggest segment, is growing 3.2 percent underlying. Neither is a crisis at 46.5 percent gross margin, but neither leaves room for the 5 percent-plus headline to survive a weaker dollar.
26 Flat revenue · operating loss

The growth brands added exactly what generics lost, and the loss came from somewhere else

Teva’s three growth brands added USD 310M between them and generic products lost USD 308M. The two almost perfectly cancel, which is why revenue was flat at USD 4,142M against USD 4,176M, down 0.8 percent. AUSTEDO grew 39.8 percent to USD 696M, AJOVY 57.8 percent to USD 243M and UZEDY 42.6 percent to USD 77M, while generics fell 12.8 percent to USD 2,103M.

The loss came from research spending. R&D was USD 970M against USD 244M, a rise of USD 726M in a quarter where revenue fell USD 34M. That took R&D to 23.4 percent of revenue from 5.8 percent and turned an operating profit of USD 455M into an operating loss of USD 231M.

Everything between gross profit and operating income moved against the company at once. Legal settlements and loss contingencies rose to USD 230M from USD 166M, and selling and marketing to USD 717M from USD 654M. Gross margin actually improved 164 basis points to 52.0 percent, so the trading business was healthier and the result was still a loss.

Non-GAAP earnings tell the sharpest version. Non-GAAP net income attributable to Teva fell to USD 21M from USD 769M and non-GAAP diluted earnings per share to USD 0.02 from USD 0.66. Reported diluted loss per share was USD 0.49 against earnings of USD 0.24. Teva still raised full-year revenue guidance to USD 16.5 to 16.85B.

26Mkt cap Teva NYSE TEVA · Mkt cap USD 43.66B
Total revenue
USD 4.14B
-0.8%reported+2.4%gross profit
Revenue added
-USD 34M-0.8%
From USD 4.18B, -0.8%
Profit margin
-5.6%-1,650bp
Operating margin, from +10.9%
R&D expense
USD 970M+297.5%
23.4% of revenue, from 5.8%
Non-GAAP EPS
USD 0.02-97.0%
Reported -USD 0.49, from USD 0.24
Gross margin
52.0%+164bp
Gross profit USD 2.15B
Sales by region · as reported
USD 4.14B Q2 REVENUE
United StatesUSD 1.7B · -4.7%41.1%
EuropeUSD 1.26B · -2.7%30.5%
Other activitiesUSD 627M · n/d15.1%
International MarketsUSD 550M · +11.1%13.3%
Product · worldwide, year on year
Generic productsall three segmentsUSD 2.1B-12.8%
AUSTEDOneuroscienceUSD 696M+39.8%
AJOVYmigraineUSD 243M+57.8%
COPAXONElegacy brandUSD 118M-0.8%
UZEDYneuroscienceUSD 77M+42.6%
The swing · year on year
Generic products-USD 308M
AUSTEDO, AJOVY, UZEDY+USD 310M
The three growth brands added USD 310M and generics lost USD 308M, so revenue barely moved. The loss came from R&D, up USD 726M.
Segment · revenue and profit
United Statessegment profit -USD 76MUSD 1.7B-4.7%
Europesegment profit USD 367MUSD 1.26B-2.7%
International Marketssegment profit USD 99MUSD 550M+11.1%
Other activitiesAPI and otherUSD 627M
Total revenuefrom USD 4,176MUSD 4.14B-0.8%
Income statement · year on year
Gross profitfrom USD 2,102MUSD 2.15B+2.4%
Research and developmentfrom USD 244MUSD 970M+297.5%
Selling and marketingfrom USD 654MUSD 717M+9.6%
Legal settlementsfrom USD 166MUSD 230M+38.6%
Operating incomefrom USD 455M-USD 231M
What grew
  • AJOVY up 57.8 percent to USD 243M worldwide
  • UZEDY up 42.6 percent to USD 77M
  • AUSTEDO up 39.8 percent to USD 696M
  • International Markets up 11.1 percent to USD 550M, the only segment growing
What shrank
  • Generic products down 12.8 percent to USD 2,103M worldwide
  • United States segment down 4.7 percent, segment profit of -USD 76M
  • Europe segment down 2.7 percent to USD 1,263M
  • Non-GAAP net income USD 21M against USD 769M
On the clock · next quarter
  • GuidanceRevenue raised to USD 16.5 to 16.85B from USD 16.4 to 16.8B
  • GuidanceAUSTEDO raised to USD 2,450 to 2,600M
  • GuidanceAJOVY raised to USD 850 to 870M from USD 750 to 790M
  • WatchR&D whether USD 970M was a one-off charge or a new base
Cost of sales USD 1.99B from USD 2.07B/General and administrative USD 317M from USD 305M/Financial expenses net USD 224M from USD 252M/Income taxes USD 121M against a USD 78M benefit/Net loss attributable -USD 576M from +USD 282M/Diluted shares 1,165M
Synopulse
The Top Line · Q2 2026
Q2 2026 results release, consolidated statements and segment tables · extracted 20 August 2026
What decides the next twelve months Whether the R&D line comes back down. Strip the charge out and Teva had a decent quarter: gross margin up 164 basis points, three brands compounding between 39 and 58 percent, and full-year revenue guidance raised. The structural problem is unchanged and slow. Generics are USD 2.1 billion of revenue falling 12.8 percent a year, and the brands replacing them added USD 310 million this quarter against USD 308 million lost, which keeps the company flat rather than growing.
27 Sales +8% · +7% constant fx

Equipment is a sixth of surgical and produced half its growth

Alcon grew 8 percent to $2,782 million, and 7 percent at constant currency. Inside Surgical, which grew 8 percent to $1,570 million, the contributions are wildly uneven. Equipment and other grew 26 percent, adding $57 million, while Implantables grew 2 percent, adding $10 million. Equipment is 17.8 percent of the segment and delivered roughly half its growth.

Implantables is the line to watch. At $466 million it is the second largest in Surgical and grew just 1 percent at constant currency. Intraocular lenses grew 2 percent at constant currency on the strength of PanOptix Pro, and Alcon names two offsets explicitly: competitive pressures, and lower sales in surgical glaucoma.

Vision Care carried the other half of the company and grew 8 percent to $1,212 million, 7 percent at constant currency. Ocular health was the stronger line at 13 percent, reaching $486 million, against contact lenses at 5 percent and $726 million.

Across the half the pattern holds. Net sales were $5,467 million against $5,028 million, up 9 percent reported and 7 percent at constant currency, with a 2 point currency benefit. Equipment and other again led at 26 percent reported and 24 percent constant currency.

27Mkt cap Alcon NYSE ALC · SIX ALC · Mkt cap USD 35.89B
Total revenue
USD 2.78B
+8%reported+7%const fx
Segment and line · year on year
Surgical USD 1.57B +8%Vision Care USD 1.21B +8%
SurgicalsegmentUSD 1.57B+8%
Vision CaresegmentUSD 1.21B+8%
Consumablesin SurgicalUSD 825M+6%
Contact lensesin Vision CareUSD 726M+5%
Ocular healthin Vision CareUSD 486M+13%
Implantablesin SurgicalUSD 466M+2%
Equipment, otherin SurgicalUSD 279M+26%
The swing · year on year
Implantables added+USD 10M
Equipment and other added+USD 57M
Equipment is 17.8% of Surgical and produced about half its growth. Implantables is 29.7% of Surgical and added USD 10M, growing 1% at constant currency.
Quarter · reported and constant currency
Consumablescc +5%USD 825M+6%
Contact lensescc +5%USD 726M+5%
Ocular healthcc +12%USD 486M+13%
Implantablescc +1%USD 466M+2%
Equipment and othercc +25%USD 279M+26%
Half year · reported and constant currency
Total Surgicalcc +7%USD 3.03B+9%
Total Vision Carecc +7%USD 2.44B+9%
Consumablescc +5%USD 1.59B+7%
Contact lensescc +4%USD 1.46B+6%
Net salescc +7%USD 5.47B+9%
Fastest lines
  • Equipment and other 26 percent reported and 25 percent at constant currency
  • Ocular health 13 percent reported and 12 percent at constant currency
  • Consumables 6 percent reported and 5 percent at constant currency
  • Contact lenses 5 percent reported and at constant currency
Implantables detail
  • Intraocular lenses up 2 percent at constant currency
  • PanOptix Pro named as the driver of IOL growth
  • Competitive pressures named by Alcon as an offset
  • Surgical glaucoma lower sales, named as an offset
On the clock · next quarter
  • WatchImplantables 1 percent constant currency, competitive pressure named explicitly
  • WatchEquipment 26 percent growth on a small base, half of Surgical’s increase
  • WatchCurrency 1 point of benefit in the quarter and 2 points in the half
Total Surgical USD 1.57B from USD 1.46B, +8% reported and +7% at constant currency/Total Vision Care USD 1.21B from USD 1.12B, +8% and +7%/Implantables USD 466M from USD 456M, +2% and +1%/Consumables USD 825M from USD 777M/Equipment and other USD 279M from USD 222M/Contact lenses USD 726M from USD 692M
Synopulse
The Top Line · Q2 2026
Q2 and H1 2026 results, net sales by segment · extracted 20 August 2026
What decides the next twelve months Implantables. It is $466 million of the highest-value revenue Alcon has, and it grew 1 percent at constant currency while everything around it grew between 5 and 26 percent. Alcon names competitive pressure directly, which is unusual candour, and PanOptix Pro is currently holding the line rather than extending it. Equipment growing 26 percent is welcome but it is a $279 million business and capital equipment cycles turn.
28 Orders +11.1% · revenue +3.5%

Orders grew three times faster than revenue, and free cash flow was negative without tariff refunds

Organic orders grew 11.1 percent against organic revenue at 3.5 percent, a book-to-bill of 1.15 times and a backlog of $23.9 billion. Demand is running well ahead of what GE HealthCare is converting, which is the same signal Siemens Healthineers is showing four places above at 1.19 times.

The reported profitability is flattered. Free cash flow was $68 million, an improvement of $61 million, and GE HealthCare states it includes $107 million of refunds for IEEPA tariffs incurred in 2025 and 2026. Strip those out and cash flow for the quarter was negative by roughly $39 million.

The same qualifier runs through the margin. Adjusted EBIT was $750 million at a 14.2 percent margin, down 40 basis points, and includes $23 million of 2026 tariff refunds. Adjusted EPS of $1.13 was up 6.6 percent and includes $0.04 of the same benefit. The company also notes that both measures exclude a further $106 million and $0.18 of refunds relating to 2025 tariffs.

Strategically the quarter was about scale and consolidation. GE HealthCare signed a $500 million Care Alliance with Catholic Health, strengthened a theranostics collaboration in Germany, and reported Flyrcado on track for a $500 million annual opportunity with Vizamyl at $200 million by 2028. It is also consolidating a new AIS segment and Global Markets region.

28Mkt cap GE HealthCare NASDAQ GEHC · Mkt cap USD 33.94B
Total revenue
USD 5.3B
+3.5%organic+11.1%orders
Revenue added
+USD 0.2B
Approximate, source states USD 5.3B
Profit margin
14.2%-40bp
Adjusted EBIT margin, USD 750M
Adjusted EPS
USD 1.13+6.6%
Includes USD 0.04 of tariff refunds
The swing · orders against revenue
Organic revenue growth+3.5%
Organic orders growth+11.1%
A book-to-bill of 1.15x and a backlog of USD 23.9B. Orders are growing three times faster than the revenue being recognised against them.
The quarter · headline measures
Revenuesorganic +3.5%USD 5.3B
Organic orders growthbook-to-bill 1.15x+11.1%
Backlogend of quarterUSD 23.9B
Adjusted EBITmargin 14.2%, -40bpUSD 750M
Adjusted EPS+6.6% year on yearUSD 1.13
Tariff refunds inside the numbers
Free cash flow, reportedimprovement of USD 61MUSD 68M
Tariff refunds in cash flow2025 and 2026 IEEPAUSD 107M
Free cash flow, excludingderived-USD 39M
Tariff refunds in adjusted EBIT2026 onlyUSD 23M
Refunds excluded from adjusted2025, and USD 0.18 of EPSUSD 106M
Precision care
  • Catholic Health Care Alliance signed, about USD 500M across several care areas and services
  • Theranostics collaboration strengthened with leading academic partners in Germany
  • Flyrcado on track for a USD 500M annual opportunity by 2028
  • Vizamyl on track for USD 200M by 2028
Growth and optimisation
  • Orders driven by commercial execution and adoption of new products across all segments and regions
  • Gadolinium-free MR contrast Phase 2/3 progressing with high recruitment in the US and Europe
  • Price and cost actions incremental measures beginning to take effect against inflation
  • Segment change consolidating a new AIS segment and Global Markets region
On the clock · next quarter
  • WatchFree cash flow negative by about USD 39M once tariff refunds are removed
  • WatchBacklog conversion USD 23.9B and a book-to-bill of 1.15x to work through
  • WatchAdjusted EBIT margin down 40 basis points even with USD 23M of refunds inside it
Revenues USD 5.3B, organic growth 3.5%/Organic orders growth 11.1%, book-to-bill 1.15x, backlog USD 23.9B/Adjusted EBIT USD 750M, margin 14.2%, down 40 basis points/Adjusted EPS USD 1.13, up 6.6%/Free cash flow USD 68M, an improvement of USD 61M/Adjusted EBIT includes USD 23M and adjusted EPS USD 0.04 of refunds for IEEPA tariffs incurred in 2026
Synopulse
The Top Line · Q2 2026
Q2 2026 consolidated performance summary and growth strategy slides · extracted 20 August 2026
What decides the next twelve months Whether the backlog converts before the refunds stop. A book-to-bill of 1.15 times and $23.9 billion of backlog is a genuine forward position, and the margin and cash flow that sit against it today are propped up by tariff refunds that do not recur. Adjusted EBIT margin fell 40 basis points with $23 million of refunds already inside it, which is the honest read on operating performance this quarter.
29 Margin +4.0pp on tariff refunds

The margin rose four points and Philips says the tariff refund was worth 4.2

Adjusted EBITA margin improved to 16.4 percent from 12.4 percent, a gain of four points. Philips states plainly that this includes a tariff refund benefit of effectively 4.2 percent, and that adjusted EBITA excluding the refund slightly decreased, held back by cost inflation and higher tariffs against higher sales and productivity measures. The entire improvement, and slightly more, is a refund.

Sales were €4,360 million, up 1 percent nominally and 4 percent on a comparable basis, with growth across all segments: Personal Health up 8 percent comparable, Diagnosis and Treatment up 2 percent and Connected Care up 2 percent. Comparable order intake, however, was minus 1 percent against plus 6 percent a year earlier.

That order number is the outlier in the medtech block. Siemens Healthineers is running a book-to-bill of 1.19 and GE HealthCare 1.15, both with backlogs building faster than revenue. Philips is the one taking in less work than a year ago.

Reported profit rose sharply for reasons beyond trading. Income from operations was €609 million against €400 million, helped by the refund, higher sales and a swing in restructuring and acquisition items from a €20 million charge to €86 million of income, which included a €99 million gain on a divested business against €50 million of portfolio realignment and €50 million of Respironics charges. Net income was €386 million against €240 million.

29Mkt cap Philips NYSE PHG · AMS PHIA · Mkt cap USD 26.99B
Total revenue
EUR 4.36B
+1%nominal+4%comparable
Revenue added
+EUR 22M
From EUR 4.34B, comparable +4%
Profit margin
16.4%+400bp
Adjusted EBITA margin, 4.2pp of it refunds
R&D expense
EUR 484M+20.4%
11.1% of sales, from 9.3%
Adjusted EPS
EUR 0.49+36.1%
Reported diluted EUR 0.40, from EUR 0.25
Gross margin
49.3%+561bp
Gross margin EUR 2.15B
Profit measures · year on year
Adjusted EBITDA20.9% of salesEUR 910M+21.8%
Adjusted EBITA16.4% of salesEUR 717M+32.8%
EBITA16.0% of salesEUR 697M+53.9%
Income from operations14% of salesEUR 609M+52.3%
Net incomefrom €240MEUR 386M+60.8%
The swing · margin bridge
Underlying margin change-0.2pp
Tariff refund benefit+4.2pp
Adjusted EBITA margin went from 12.4% to 16.4%. Philips attributes 4.2 points to the tariff refund and says adjusted EBITA excluding it slightly decreased.
Comparable sales by segment
Personal Healthcomparable+8%
Diagnosis and Treatmentcomparable+2%
Connected Carecomparable+2%
Group comparable salesnominal +1%+4%
Comparable order intakefrom +6%-1%
Income statement · year on year
Salesfrom EUR 4.34BEUR 4.36B+1%
Income from operationsfrom EUR 400MEUR 609M+52%
Financial expenses netfrom EUR 57MEUR 62M+9%
Income tax expensefrom EUR 95MEUR 160M+68%
Net incomefrom EUR 240MEUR 386M+61%
What management attributed
  • Income from operations up €209M on the tariff refund, higher sales and lower restructuring charges
  • Adjusted EBITA excluding the refund it slightly decreased on cost inflation and higher tariffs
  • Restructuring and acquisition income of €86M against charges of €20M a year ago
  • Income tax expense up €65M, including the tax impact of the divestment
Inside the €86M of income
  • Divestment gain €99M on the sale of a divested business
  • Portfolio realignment €50M of charges
  • Respironics €50M of related charges
  • Net effect a €106M swing against the prior-year quarter
On the clock · next quarter
  • WatchOrder intake minus 1 percent comparable, against +6 percent a year ago
  • WatchUnderlying margin adjusted EBITA excluding the refund slightly decreased
  • WatchTariffs higher tariffs named as a headwind alongside the refund benefit
Reported in euros/Sales €4,360M from €4,338M, nominal +1% and comparable +4%/Comparable order intake -1% from +6%/Income from operations €609M from €400M, 14% of sales from 9%/EBITA €697M, 16.0% of sales from 10.5%/Adjusted EBITA €717M, 16.4% from 12.4%
Synopulse
The Top Line · Q2 2026
Q2 2026 second quarter highlights and key data · extracted 20 August 2026
What decides the next twelve months Order intake. A four point margin improvement that the company itself attributes almost entirely to a tariff refund is not a change in the business, and Philips says as much: excluding the refund, adjusted EBITA slightly decreased. What matters more is the minus 1 percent comparable order intake, because Siemens and GE HealthCare are both building backlog at book-to-bill above 1.15 in the same quarter and Philips is not.
30 Sales +5% · adjusted EPS flat

Most of the earnings increase is a smaller loss from a business being exited

Net income rose 38 percent to $126 million from $91 million. Income from continuing operations rose 11 percent, contributing $13 million. The loss from discontinued operations narrowed from $31 million to $9 million, contributing $22 million. Roughly 63 percent of the earnings increase comes from a business Baxter is on the way out of.

On the continuing business the picture is flat. Sales grew 5 percent to $2,960 million while cost of sales grew 6 percent, so gross margin slipped 40 basis points to 34.9 percent, the lowest on any card in this edition. Adjusted operating income was $421 million against $423 million, unchanged, and adjusted diluted EPS from continuing operations fell 5 percent to $0.56.

The costs Baxter did control were the discretionary ones. Selling and administrative expenses grew 2 percent, well below sales, taking them to 24.8 percent of revenue from 25.6 percent. Research and development fell 4 percent to $129 million, or 4.4 percent of sales from 4.8 percent, which is the lowest research intensity in this edition.

Below the line, both interest and tax took more. Net interest expense rose 10 percent to $64 million and the effective tax rate rose to 14.6 percent from 8.3 percent. Reported operating income still grew 14 percent to $217 million, taking the operating margin from 6.8 percent to 7.3 percent.

30Mkt cap Baxter NYSE BAX · Mkt cap USD 13.77B
Total revenue
USD 2.96B
+5%reported0%adj op income
Revenue added
+USD 150M
From USD 2.81B, adjusted operating flat
Profit margin
7.3%+50bp
Operating margin, from 6.8%
R&D expense
USD 129M-4%
4.4% of sales, from 4.8%
Adjusted EPS
USD 0.540%
Continuing operations USD 0.56, -5%
Gross margin
34.9%-40bp
Gross margin USD 1.03B
Income statement · year on year
Net salesfrom $2,810MUSD 2.96B+5%
Cost of salesfrom $1,819MUSD 1.93B+6%
Gross margin34.9% of salesUSD 1.03B+4%
SG&A24.8% of salesUSD 735M+2%
Adjusted operating incomefrom $423MUSD 421M0%
Operating income7.3% of salesUSD 217M+14%
R&D4.4% of salesUSD 129M-4%
The swing · where the earnings came from
From continuing operations+USD 13M
From a smaller discontinued loss+USD 22M
Net income rose USD 35M. Continuing operations contributed USD 13M and the narrowing of the discontinued loss, from USD 31M to USD 9M, contributed USD 22M.
Reported against adjusted
Operating income, reportedfrom USD 191MUSD 217M+14%
Operating income, adjustedfrom USD 423MUSD 421M0%
Net income, reportedfrom USD 91MUSD 126M+38%
Net income, adjustedfrom USD 276MUSD 281M+2%
Adjusted diluted EPSfrom USD 0.54USD 0.54
Ratios · % of net sales
Gross marginfrom 35.3%34.9%
Selling and administrativefrom 25.6%24.8%
Research and developmentfrom 4.8%4.4%
Operating marginfrom 6.8%7.3%
Effective tax ratefrom 8.3%14.6%
What moved up
  • Net sales up 5 percent to USD 2.96B
  • Operating income up 14 percent to USD 217M, margin 7.3 percent from 6.8 percent
  • Income before taxes up 19 percent to USD 158M
  • Reported diluted EPS USD 0.24 against USD 0.18, up 33 percent
What moved down
  • Gross margin 34.9 percent from 35.3 percent, cost of sales up 6 percent
  • Research and development down 4 percent to USD 129M
  • Adjusted EPS from continuing operations USD 0.56 against USD 0.59, down 5 percent
  • Adjusted operating income USD 421M against USD 423M, flat
On the clock · next quarter
  • WatchDiscontinued operations the USD 22M swing that carried most of the earnings increase runs out
  • WatchGross margin 34.9 percent and falling, cost of sales outgrowing sales
  • WatchR&D cut 4 percent to 4.4 percent of sales, the lowest intensity in this edition
Cost of sales USD 1.93B, +6%, against sales +5%/Other operating income net USD 49M from USD 52M/Net interest expense USD 64M, +10%/Other income net USD 5M/Income from continuing operations before taxes USD 158M, +19%/Income tax expense USD 23M from USD 11M, effective rate 14.6% from 8.3%
Synopulse
The Top Line · Q2 2026
Q2 2026 unaudited condensed consolidated statements of income · extracted 20 August 2026
What decides the next twelve months Whether anything grows once the exit is finished. Adjusted operating income was flat and adjusted EPS from continuing operations fell 5 percent, so on the business Baxter intends to keep, this quarter went backwards. Gross margin at 34.9 percent is the thinnest in this edition and it is still narrowing, and R&D was cut to 4.4 percent of sales to help hold the operating line. That is a defensible move once. It is not a strategy.